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Active, not recruiting Observational

Cervical Lordosis: Imaging Position and Measurement

NCT07541586 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2025-01-01
Last updated
2026-05-06

Condition(s) studied

Cervical LordosisLordosis; PosturalRadiographic StudyRadiographic OutcomesMagnetic Resonance Imaging (MRI)Supine Position

Investigational drug(s) / intervention(s)

No intervention

No intervention: This is an observational study with no assigned intervention. Groups are defined based on the imaging modality (standing radiograph vs supine MRI).

Study summary

This retrospective cross-sectional study aims to compare cervical lordosis measurements obtained from standing lateral radiographs and supine magnetic resonance imaging (MRI) in individuals without structural cervical pathology. The study also evaluates the independent contribution of T1 slope to cervical alignment and investigates whether imaging modality significantly alters measured lordosis values.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Adults aged 18 to 65 years * Availability of standing lateral cervical radiograph or supine cervical MRI performed during the registry period * No structural cervical pathology affecting sagittal alignment * Images of adequate quality for radiographic measurement * Neutral standing radiograph position for Standing Radiograph Group * Standard supine acquisition for Supine MRI Group Exclusion Criteria: * Prior cervical spine surgery * Cervical fracture, dislocation, or whiplash history * Primary or metastatic cervical malignancy * Congenital vertebral anomaly including Klippel-Feil syndrome, os odontoideum, hemivertebra, block vertebra, or atlantoaxial instability * Spinal deformity or postural disorder likely to affect cervical alignment, including scoliosis, hyperkyphosis, or Scheuermann disease * Advanced degenerative cervical disease, including severe spondylosis, cervical spinal stenosis, OPLL, or DISH * Inflammatory or autoimmune rheumatologic disease affecting the spine * Neuromuscular or neurologic disorders affecting posture or alignment * Inadequate image quality, major artifact, or improper positioning

Primary outcome measure(s)

  • Difference in Cobb C2-C7 angle between standing radiographs and supine MRI — Baseline retrospective image assessment
    Cobb C2-C7 angle measured using standard endplate-based methodology on standing lateral cervical radiographs and supine cervical MRI. The primary comparison evaluates the difference in cervical lordosis between imaging modalities obtained under weight-bearing and non-weight-bearing conditions.
  • Difference in Cobb C1-C7 angle between standing radiographs and supine MRI — Baseline retrospective image assessment
    Cobb C1-C7 angle measured on standing lateral radiographs and supine MRI using standard radiographic techniques. This outcome assesses global cervical lordosis differences between imaging modalities.

Trial sites (1)

FacilityCityRegionStatus
İstanbul Medipol University Istanbul Turkey (Türkiye)
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07541586 on ClinicalTrials.gov ↗ ← All trials in Turkey