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Recruiting Observational

Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction

NCT07523854 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2026-01-23
Last updated
2026-04-15

Condition(s) studied

Anterior Cruciate Ligament Reconstruction RehabilitationStrength OutcomesAnterior Cruciate Ligament (ACL) Reconstruction Surgery

Study summary

This prospective observational study will compare recovery after anterior cruciate ligament reconstruction using quadriceps tendon autograft or hamstring tendon autograft. The main goal is to examine differences in knee muscle strength recovery during the early and mid-term postoperative period. Participants aged 13 to 45 years who undergo unilateral ACL reconstruction and meet the eligibility criteria will be followed at Hacettepe University. Knee extensor and flexor strength will be assessed using isometric testing at postoperative weeks 4, 8, and 12 and month 6, and with isokinetic concentric testing at months 3 and 6. Functional outcomes and kinesiophobia will also be evaluated at month 6 using IKDC, KOOS, and the Tampa Scale for Kinesiophobia. All participants will receive the same standard postoperative rehabilitation program under physiotherapist supervision. The study aims to clarify whether graft type is associated with different patterns of muscle strength recovery and functional improvement after ACL reconstruction

Eligibility

Sex
ALL
Min age
13 Years
Max age
45 Years
Healthy volunteers
No
Inclusion Criteria: * Age 13 to 45 years * Undergoing anterior cruciate ligament reconstruction with either hamstring tendon autograft or quadriceps tendon autograft * Unilateral anterior cruciate ligament injury * Complete ACL tear with accompanying minimal collateral ligament injury and first-degree meniscal tear * Tegner Activity Score of 5 or higher * Willingness to participate in the study Exclusion Criteria: * Anterior cruciate ligament reconstruction with patellar tendon autograft or allograft * Revision surgery * Systemic or neurological disease * Multiple ligament injuries * Grade III lateral or medial collateral ligament tear or significant articular cartilage lesion * Failure to regularly attend the rehabilitation program during the first 3 postoperative months * History of lower extremity injury in the contralateral limb within the last 12 months * Hypertension, cardiovascular disease, peripheral vascular disease, history of deep vein thrombosis, neurological disease, systemic inflammation, diabetes, cancer, or obesity

Primary outcome measure(s)

  • Isometric Quadriceps Muscle Strengt — Postoperative weeks 4, 8, and 12, and month 6
    Maximum voluntary isometric quadriceps strength measured with an IsoMed 2000 dynamometer at 60° of knee flexion. The highest value from 3 maximal 5-second contractions will be recorded and normalized to body weight (Nm/kg).
  • Isometric Hamstring Muscle Strength — Postoperative weeks 4, 8, and 12, and month 6
    Maximum voluntary isometric hamstring strength measured with an IsoMed 2000 dynamometer at 60° of knee flexion. The highest value from 3 maximal 5-second contractions will be recorded and normalized to body weight (Nm/kg)

Trial sites (1)

FacilityCityRegionStatus
Hacettepe University Ankara Turkey (Türkiye) Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07523854 on ClinicalTrials.gov ↗ ← All trials in Turkey