Effectiveness of Thoracoabdominal Nerve Block (M-TAPA) on Postoperative Pain Relief in Laparoscopic Hysterectomy

Condition(s) studied

Investigational drug(s) / intervention(s)

Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA): Under ultrasound guidance, a 22-gauge peripheral block needle is inserted at the costochondral angle (9th-10th ribs). After confirming the position, 20 ml of 0.25% bupivacaine is injected bilaterally into the lower part of the chondrium.

Study summary

This study aims to investigate the effectiveness of a specific regional anesthesia technique, the Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA), on reducing pain after laparoscopic hysterectomy surgery. Hysterectomy is a common major surgical procedure, and managing postoperative pain is crucial for patient comfort and faster recovery.

Participants will be randomly assigned to one of two groups:

The M-TAPA Group: Patients will receive the nerve block using a local anesthetic (bupivacaine) before the surgery begins.

The Control Group: Patients will receive standard postoperative pain management without the nerve block.

The primary goal is to determine if the M-TAPA block reduces the total amount of opioid (morphine) used by patients in the first 24 hours after surgery. The researchers will also evaluate pain scores (NRS), the time until the first request for additional pain medication, patient satisfaction, and any side effects like nausea or vomiting

Eligibility

Primary outcome measure(s)

• Morphine consumption — First 24 hours postoperatively
  Total amount of morphine (mg) used via Patient-Controlled Analgesia (PCA)

Trial sites (1)

More Istinye University trials in Turkey

Other trials for the same condition