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Recruiting Observational

Transcutaneous pO₂ Monitoring in PICU

NCT07478380 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2026-03-10
Last updated
2026-03-17

Condition(s) studied

Pediatric Critical Illness

Study summary

Arterial blood gas analysis is commonly used in pediatric intensive care units (PICUs) to assess oxygen and carbon dioxide levels in critically ill children. However, arterial blood sampling is invasive, can be painful, and may need to be repeated frequently. Transcutaneous monitoring provides a noninvasive method to continuously measure oxygen (pO₂) and carbon dioxide (pCO₂) levels through the skin, but its accuracy in critically ill pediatric patients requires further evaluation.

The purpose of this observational study is to compare transcutaneous pO₂ and pCO₂ measurements with arterial blood gas values in pediatric intensive care unit patients. By analyzing paired measurements obtained simultaneously during routine clinical care, this study aims to evaluate the agreement between transcutaneous and arterial measurements, with a particular focus on whether transcutaneous pO₂ can serve as a reliable alternative to arterial sampling.

The results of this study may help clarify the role of transcutaneous monitoring in pediatric intensive care and may contribute to reducing the need for invasive blood sampling in selected patients.

Eligibility

Sex
ALL
Min age
1 Month
Max age
18 Years
Healthy volunteers
No
Eligibility Criteria Inclusion Criteria: * Age between 1 month and 18 years * Admission to the Pediatric Intensive Care Unit (PICU) * Presence of an arterial catheter allowing arterial blood gas (ABG) sampling * Simultaneous or paired transcutaneous pCO₂ and pO₂ monitoring available * Hemodynamically stable at the time of measurement Exclusion Criteria: * Severe skin disease, burns, or local skin infection at the transcutaneous sensor site * Severe peripheral perfusion impairment (e.g., refractory shock or high-dose vasopressor support) * Congenital or acquired conditions interfering with accurate transcutaneous measurements * Technical failure or inability to obtain reliable transcutaneous readings * Missing or incomplete paired ABG-transcutaneous measurement data

Primary outcome measure(s)

  • Agreement Between Transcutaneous pO₂ and Arterial pO₂ — At the time of each paired transcutaneous monitoring and arterial blood gas measurement during PICU admission (up to 28 days)
    Agreement between transcutaneous oxygen partial pressure (Tc pO₂) and arterial oxygen partial pressure (PaO₂) obtained from arterial blood gas analysis in pediatric intensive care unit patients.

Trial sites (1)

FacilityCityRegionStatus
Göztepe Prof. Dr. Süleyman Yalçın City Hospital Istanbul Kadıkoy Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07478380 on ClinicalTrials.gov ↗ ← All trials in Turkey