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Recruiting Not applicable

The Effect of Virtual Reality Therapy on Upper Extremity Functions in Subacute Stroke Patients Receiving Rehabilitation

NCT07299162 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2025-08-15
Last updated
2026-01-28

Condition(s) studied

StrokeHemiplegia and/or Hemiparesis Following Stroke

Investigational drug(s) / intervention(s)

Virtual RealityConventional rehabilitationAction observation therapy

Virtual Reality: Camera controlled virtual reality games for upper extremity

Conventional rehabilitation: Personalized conventional exercises for hemiparesis after stroke

Action observation therapy: Rehabilitation method that involves patients watching video recordings of purposeful upper extremity movements designed for daily life activities followed by physically attempting the same movements.

Study summary

Stroke ranks second among the leading causes of death worldwide and third among the causes of disability. In stroke patients, motor impairment typically affects facial movements and the upper and lower extremities unilaterally. Upper extremity involvement, in particular, negatively impacts patients' activities of daily living, such as eating and dressing. Various rehabilitation methods are used to improve the function of the paretic upper extremity in stroke patients. Action Observation Therapy and Virtual Reality are among the rehabilitation approaches currently used to support upper extremity rehabilitation.

In our study, patients will be randomly divided into two groups: one group will receive conventional rehabilitation and Action Observation Therapy, while the other group will additionally receive Virtual Reality therapy. This study aims to investigate the contribution of Virtual Reality therapy, when added to conventional rehabilitation and Action Observation Therapy, to the recovery of the paretic upper extremity in patients with subacute stroke.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients over the age of 18 * Patients in the subacute phase of stroke (between 6 weeks and 6 months post-stroke) * Patients with a first-ever stroke * Brunnstrom stage 3 or above for both upper extremity and hand * Mini-Mental State Examination (MMSE) score \>=20 No major medical condition that would prevent participation in the treatment Exclusion Criteria: * Presence of pain in the paretic shoulder severe enough to prevent exercise * History of bilateral stroke * Patients with global aphasia and/or cognitive impairment that significantly affects treatment compliance * Patients with severe visual impairment * Presence of unilateral spatial neglect * Inability to maintain sitting balance * Modified Ashworth Scale \> 4 in the hemiplegic arm

Primary outcome measure(s)

  • Fugl-Meyer Upper Extremity — From enrollment to the 1 months after treatment
    The Fugl-Meyer Assessment for Upper Extremity (FMA-UE) is a standardized scale used to assess motor recovery of the upper limb in post-stroke patients. It evaluates voluntary movement, reflex activity, coordination, and speed. The scale consists of 33 items, and the total score ranges from 0 to 66, with 0 indicating no motor function and 66 representing normal motor function. A Turkish validity and reliability study has also been conducted for this scale.

Trial sites (1)

FacilityCityRegionStatus
Istanbul Physical Therapy and Rehabilitation Training and Research Hospital Istanbul Bahçelievler Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07299162 on ClinicalTrials.gov ↗ ← All trials in Turkey