Motor Imagery and Action Observation for Gait Function in MS

Condition(s) studied

Investigational drug(s) / intervention(s)

Action Observation + Motor Imagery: Participants will watch videos showing walking actions and will be instructed to mentally simulate the movement.

Nature Video: Participants will watch a video of nature scenes.

Study summary

This study will investigate whether mentally simulating walking movements while watching others walk can improve walking performance in individuals with Multiple Sclerosis (MS). Participants will be divided into two groups: one group will watch walking videos and imagine themselves walking, while the other group will watch nature scenes. The study will measure muscle activity and walking patterns to assess the effects. The results may help support the use of mental practice techniques to improve mobility in people with MS.

Eligibility

Primary outcome measure(s)

• Change in Tibialis Anterior and Gastrocnemius Medialis Muscle Activity Amplitude — Before and immediately after the intervention
  Change in muscle activity amplitude (microvolts, µV) of tibialis anterior and gastrocnemius medialis during gait initiation measured by surface EMG.
• Change in Tibialis Anterior and Gastrocnemius Medialis Muscle Activity Onset Latency — Before and immediately after the intervention.
  Change in onset latency (milliseconds, ms) of tibialis anterior and gastrocnemius medialis muscle activation during gait initiation measured by surface EMG.
• Change in Step Length — Before and immediately after the intervention
  Change in step length (centimeters, cm) during gait initiation measured by the GAITRite system.
• Change in Step Time — Before and immediately after the intervention
  Change in step time (seconds, s) during gait initiation measured by the GAITRite system.
• Change in Step Width — Before and immediately after the intervention
  Change in step width (centimeters, cm) during gait initiation measured by the GAITRite system.
• Change in Double Support Period — Before and immediately after the intervention
  Change in double support period (percentage of gait cycle, %) during gait initiation measured by the GAITRite system.
• Change in Gait Velocity — Before and immediately after the intervention
  Change in gait velocity (centimeters per second, cm/s) during gait initiation measured by the GAITRite system.
• Change in Cadence — Before and immediately after the intervention
  Change in cadence (steps per minute, steps/min) during gait initiation measured by the GAITRite system.

Trial sites (1)

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