Effect of Vitamin D Deficiency on the Frequency and Severity of Spinal Anesthesia-Induced Hypotension in Pregnant Women Undergoing Cesarean Section

Condition(s) studied

Investigational drug(s) / intervention(s)

Intraoperative Hemodynamic Monitoring: Continuous intraoperative monitoring of systolic blood pressure and heart rate following spinal anesthesia. Vasopressor usage and total fluid administration will be recorded.

Study summary

Spinal anesthesia-induced hypotension remains a common and significant complication during cesarean sections, posing risks for both mother and fetus. Vitamin D deficiency, frequently observed in pregnant women, is associated with altered vascular function and potential hemodynamic instability. This prospective observational study aims to investigate whether vitamin D deficiency is associated with an increased incidence and severity of spinal anesthesia-induced hypotension in pregnant women undergoing elective cesarean delivery. Vitamin D levels will be measured preoperatively, and intraoperative hemodynamic parameters will be closely monitored. The findings could contribute to improved management strategies for pregnant patients at risk of severe hypotension.

Eligibility

Primary outcome measure(s)

• Incidence of Hypotension After Spinal Anesthesia — ntraoperative (0-30 minutes after spinal anesthesia)
  Hypotension is defined as a ≥20% decrease in systolic blood pressure from baseline or an absolute systolic value \<90 mmHg. The presence or absence of hypotension will be recorded.

Trial sites (1)

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