Ireland
--:--IST
Recruiting Not applicable

Difference of Tear Ferning Between Women with and Without Menopausal.

NCT06848829 · tracked via the Priya Life Science Taiwan tracker
Phase
Not applicable
Started
2024-10-01
Last updated
2025-02-27

Condition(s) studied

Dry Eye Syndromes

Investigational drug(s) / intervention(s)

Pre-manepausal women

Pre-manepausal women: Compare tear ferning structure between pre-menopause and post-menopause women.

Study summary

Application of tear ferning test for clinical dry eye diagnosis and menopause

Eligibility

Sex
FEMALE
Min age
20 Years
Max age
65 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Aged between 20 and 65 years Exclusion Criteria: * No evident ocular diseases such as cornea, cataracts, vitreous degeneration, glaucoma, and retinopathy. * Belong to vulnerable groups(pregnancy woman, prisoner, ethical minorities, economic or educationally disadvantaged subjects, disabled individuals such as those at terminal stage of tumorigenesis, blindness, terminal ill individuals)

Primary outcome measure(s)

  • Schirmer's test — 5 minutes
    To assess tear secretion volume
  • Tear film breakup time — 20 seconds
    To assess tear quality
  • Ocular surface status — 3 minutes
    To assess ocular surface health status with lissamine green stain, health or corneal abrasion.
  • Tear ferning — 30 minutes
    crystal structure formed from tear drops on a slide be scored.
  • Menopause related hormone Enzyme-linked immunosorbent assay (ELISA) — 3 hours
    To assess FSH/LH/E2/Progesterone/Mc5AC/Lactoferrin concentration between pre- and post-manopause women.

Trial sites (1)

FacilityCityRegionStatus
Jen-Ai Hospital Taichung Taiwan Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06848829 on ClinicalTrials.gov ↗ ← All trials in Taiwan