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Clinical Trials in Taiwan / NCT06658821
Enrolling by invitation Not applicable

The Effect of LDL557 on Improving Degenerative Arthritis in the Elderly

NCT06658821 · tracked via the Priya Life Science Taiwan tracker
Sponsor
Chung Shan Medical University
Phase
Not applicable
Started
2025-02-27
Last updated
2026-08-17

Condition(s) studied

ArthritisJoint Pain

Investigational drug(s) / intervention(s)

LDL557-HK capsulePlacebo Capsule

LDL557-HK capsule: Subjects will take once a day during the experimental period. one LDL557-HK capsule(Heat-killed Lactobacillus delbrueckii subsp. lactis LDL557 1x10\^10cell) within 30 minutes before lunch.

Placebo Capsule: Subjects will take once a day during the experimental period. one placebo capsule within 30 minutes before lunch.

Study summary

This project is to conduct a clinical trial of SYNBIO TECH INC.'s LDL557 capsule for joint protection. To understand the improvement of joint discomfort and inflammation after supplementation, we hope to provide an updated choice for modern people's joint protection.

Eligibility

Sex
ALL
Min age
45 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * BMI 18-40 kg/m2; * Those with early stage degenerative arthritis symptoms judged by X-ray to be Kellgren-Lawrence Grading Scale level 1 or 2, and the physician determines that long-term treatment is not needed or WOMAC score\>2.0 or WOMAC total scale score\>12 or VAS score ≦6. Exclusion Criteria: * Smoking * alcoholism * diabetes * breastfeeding women and pregnant women. * Those consuming dietary supplements were excluded. * Those who use non-steroidal anti-inflammatory analgesics and those who have had joint surgery. * Rheumatoid arthritis. * Those who have had joint injections within 6 months. * Those with cardiovascular and cerebrovascular, rheumatoid or mental diseases. * Patients undergoing cancer treatment.

Primary outcome measure(s)

  • WOMAC — Baseline, Week 4, Week 8, and Week 12
    The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used in the evaluation of Hip and Knee Osteoarthritis. Higher scores indicate worse pain, stiffness, and functional limitations. The WOMAC measures five items for pain (score range 0-20), two for stiffness (score range 0-8), and 17 for functional limitation (score range 0-68).

Trial sites (1)

FacilityCityRegionStatus
Chung Shan Medical University Taichung Taiwan

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Other trials for the same condition

The Efficacy of Ultrasonication in Combination With Corticosteroid Intraarticular Injection for Arthritis Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06658821 on ClinicalTrials.gov ↗ ← All trials in Taiwan