Influence of Autonomy on Motor Learning in People With Parkinson's Disease

Condition(s) studied

Investigational drug(s) / intervention(s)

Autonomy supported learning: The ability of learners to participate in determining their own behaviour, which is the feedback schedule regarding their practice performance in this study.

Practice with predetermined feedback: Learners practice the motor task, while the feedback is provided according to their counterpartner

Study summary

The goal of this clinical trial is to explore the benefits of autonomy supported learning in patients with Parkinson's disease. The main questions to answer are:

* Whether autonomy supported learning can benefit motor learning in PD patients
* Whether autonomy supported learning can enhance intrinsic motivation and/ or information processing of PD patients in learning a new task.
* Whether autonomy supported learning can facilitate cortical excitability change after practicing a new task.

Participants will be recruited into two groups (Self-control group, SC; and yoked group, YK) to learn a finger-pressing trajectory matching task

* Participants in SC group will have choice over feedback schedule during trial practice
* Participants in YK group will receive feedback with no-choice during trial practice Researchers will compare the retention test performance to see if autonomy supported learning will lead to better learning effect.

Eligibility

Primary outcome measure(s)

• Performance accuracy — up to day 7
  Overall performance accuracy relative to the target waveform was assessed using root mean square error (RMSE), which is the mean difference between the target waveform and the participant's movement trajectory calculated over their actual movement time.

Trial sites (1)

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