Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Condition(s) studied
Study summary
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure. Current literature has highlighted the importance of systemic factors (such as vitamin D deficiency, osteoporosis and hypercolesterolemia) and local factors (such as the presence of nearby periapical infections or implant placement in sites with a history of endodontic failure) that affect bone health.
Hypothesis: Bone alterations-whether systemic or local-represent a risk factor for implant failure and peri-implantitis.
Objectives: To analyze implant failure and marginal bone loss in patients with local and/or systemic bone alterations compared to patients without such conditions.
Methods: Implant failures occurring in patients treated within the Master's Program in Oral Medicine, Surgery, and Implantology at the University of Barcelona (MCIO-UB) over the last 10 years will be analyzed and correlated with bone factors (local and systemic) recorded in their medical histories. Cases lacking the radiographic and clinical data necessary to conduct the study will be excluded.
Population: A total of 3,500 implants have been placed, with failure rates ranging from 4% to 8% depending on the techniques used; consequently, the study sample will consist of 192 implants. Cohorts of successful implants will be established by matching patients of the same sex and within a ±5-year age range who did not experience implant failure.
Eligibility
Primary outcome measure(s)
- Difference in the prevalence of implant failure and peri-implantitis between patients presenting with local and/or systemic alterations involving the bone. — 2013-2026
To see the differences of prevalences of all those factors affecting implants in the patients who present a success or failure of dental implants. The measurements that will be used will be all those taking into account local and systemic bone conditions and the final outcome of the implant: failure, bone loss or success.
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Odontologic Hospital of the University of Barcelona | Barcelona | Barcelona |
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Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07766707 on ClinicalTrials.gov ↗ ← All trials in Spain