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Clinical Trials in South Korea / NCT07784621
Starting soon Phase 1

A Phase 1 Clinical Trial to Evaluate the Safety and the Pharmacokinetic Drug-Drug Interaction Between HUC2A-752-A and HUC2A-752-B in Healthy Adults

NCT07784621 · tracked via the Priya Life Science South Korea tracker
Sponsor
Huons Co., Ltd
Phase
Phase 1
Started
2026-10
Last updated
2026-09-10

Condition(s) studied

Hypertension

Investigational drug(s) / intervention(s)

Losartan (COZZAR®) →Pitavastatin plus EzetemibeAll Pitavastatin trials (6) →All Ezetemibe trials (2) →

Losartan (COZZAR®): HUC2A-752-A

Pitavastatin plus Ezetemibe: HUC2A-752-B

Study summary

This study evaluates the pharmacokinetic drug-drug interactions of repeated co-administration of HUC2A-752-A and HUC2A-752-B compared to monotherapy of each agent in healthy adults

Eligibility

Sex
ALL
Min age
19 Years
Max age
64 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Healthy adult volunteers * Individuals with a body weight between 50.0 kg and 90.0 kg and a BMI between 18.5 kg/m² and 29.9 kg/m² Exclusion Criteria: * Individuals with a history or presence of clinically significant diseases of the following systems: hepatobiliary, renal, neurological, immunological, respiratory, gastrointestinal, endocrine, hematologic/oncologic, cardiovascular , musculoskeletal, urological, psychiatric, or sexual dysfunction. * Individuals with a history of gastrointestinal diseases or gastrointestinal surgeries that could affect the safety or pharmacokinetic evaluation of the investigational product. * Individuals with a history of hypersensitivity or clinically significant hypersensitivity reactions to losartan, pitavastatin, ezetimibe, angiotensin receptor blockers, statins, or any other medications.

Primary outcome measure(s)

  • AUCtau,ss — Day 15
    Area Under the Curve
  • Cmax,ss — Day 15
    Maximum concentration at steady state

Trial sites (1)

FacilityCityRegionStatus
Seoul National University Hospital Seoul Jongno-gu

More Huons Co., Ltd. trials in South Korea

Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Recruiting
Dose-Finding Study of HUC1-394 in Participants With Dry Eye Disease Recruiting
A Clinical Trial to Evaluate the Drug-drug Interactions of Co-administered 'HUC2-744-A' and 'HUC2-744-B' in Healthy Adult Volunteers Starting soon

Other trials for the same condition

Exploring Approaches With Lower Targets of Blood Pressure and Lipid for Improving Renal Outcome in Advanced Chronic Kidney Disease Recruiting
A Study to Evaluate Efficacy and Safety of HCP1803-4 in Patients With Essential Hypertension Starting soon
Comparison of Intensive Versus Standard Care & Education for Dyslipidemia in Hypertension and Diabetes Patients Recruiting
A Randomized, Double-blind, Multi-center, Active-controlled, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of THP-00101, THP-00102, and THP-00103 in Subjects With T2DM and Essential Hypertension Recruiting
CART-BP Prospective Study for Hypertension Control Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07784621 on ClinicalTrials.gov ↗ ← All trials in South Korea