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Starting soon Phase 1

A Clinical Trial to Evaluate the Drug-drug Interactions of Co-administered 'HUC2-744-A' and 'HUC2-744-B' in Healthy Adult Volunteers

NCT07784608 · tracked via the Priya Life Science South Korea tracker
Phase
Phase 1
Started
2026-09
Last updated
2026-09-10

Condition(s) studied

Drug-drug Interactions

Investigational drug(s) / intervention(s)

Atorvastatin Calcium →Telmisartan →

Atorvastatin Calcium: HUC2-744-A

Telmisartan: HUC2-744-B

Study summary

This study aims to evaluate the pharmacokinetic interactions between HUC2-744-A and HUC2-744-B following monotherapy or co-administration under multiple-dose conditions.

Eligibility

Sex
ALL
Min age
19 Years
Max age
55 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Healthy adults * Subjects with a body weight of 50 kg or more and a BMI within the range of 18.0 to 29.9 kg/m² Exclusion Criteria: * History or presence of clinically significant cardiovascular, respiratory, hepatic, renal, hematologic, gastrointestinal, endocrine, immunologic, dermatologic, neurological, or psychiatric disease * Presence of acute disease symptoms within 28 days prior to the first dosing * History of any disease that may affect drug absorption, distribution, metabolism, or excretion * Hypersensitivity or history of clinically significant hypersensitivity to atorvastatin, telmisartan, drugs containing ingredients of the same class, or other medications (e.g., aspirin, antibiotics, dihydropyridine derivatives)

Primary outcome measure(s)

  • AUCτ — Day 22
    Area Under the Curve of telmisartan, atorvastatin
  • Cmax,ss — Day 22
    Maximum concentration at steady state of telmisartan, atorvastatin

Trial sites (1)

FacilityCityRegionStatus
Korea University Anam Hospital Seoul Seongbuk-gu
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07784608 on ClinicalTrials.gov ↗ ← All trials in South Korea