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Clinical Trials in South Korea / NCT07717749
Starting soon Phase 1

A Study to Evaluate the Safety, Pharmacokinetics of AD-118 and AD-1181 in Healthy Adult Subjects

NCT07717749 · tracked via the Priya Life Science South Korea tracker
Sponsor
Addpharma Inc
Phase
Phase 1
Started
2026-07-24
Last updated
2026-07-21

Condition(s) studied

Chronic Heart Failure

Investigational drug(s) / intervention(s)

AD-118, AD-1181 →AD-118, AD-1181 →

AD-118, AD-1181: Single-dose oral administration of AD-118, according to randomized treatment sequence in a 2-period crossover design.

AD-118, AD-1181: Single-dose oral administration of AD-1181, according to randomized treatment sequence in a 2-period crossover design.

Study summary

A Study to Evaluate the Safety and Pharmacokinetics of AD-118 and AD-1181 Under Fasted Conditions in Healthy Adult Subjects

Eligibility

Sex
ALL
Min age
19 Years
Max age
64 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Body weight equal to or greater than 50kg and Body mass index (BMI) between 18.0 kg/m2 and 30.0 kg/m2 at the time of screening visit * Subjects aged 19 years or older and under 65 years at the screening visit Exclusion Criteria: * Participation in another clinical study with an investigational drug within the 6 months from scheduled first administration * Other exclusions applied

Primary outcome measure(s)

  • Area under the plasma concentration-time curve during dosing interval (AUCt) — [Time Frame: pre-dose (0hour) to 36hours]
    AUCt of AD-118
  • Maximum concentration of drug in plasma (Cmax) — Time Frame: pre-dose (0hour) to 36hours]
    Cmax of AD-118

Trial sites (1)

FacilityCityRegionStatus
H Plus Yangji Hospital Seoul South Korea

More Addpharma Inc. trials in South Korea

A Study to Evaluate the Safety and Pharmacokinetics of AD-118 and AD-1181 in Healthy Adult Subjects Starting soon
Evaluate the Pharmacokinetic Interaction and the Safety of AD-2321 and AD-2322 Starting soon
A Clinical Trial to Assess the Pharmacokinetics, Safety, and Food Effect of AD-230 in Healthy Adults Starting soon
A Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-231A and AD-231B and AD-231C Starting soon
A Clinical Trial to Evaluate the Bioequivalence of AD-116A and AD-1161 Under Fed Conditions in Healthy Adult Male Volunteers Starting soon

Other trials for the same condition

A Study to Evaluate the Safety and Pharmacokinetics of AD-118 and AD-1181 in Healthy Adult Subjects Starting soon
A Study to Learn More About How Safe Finerenone is and How Well it Works in Adults With Chronic Heart Failure in South Korea Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07717749 on ClinicalTrials.gov ↗ ← All trials in South Korea