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Clinical Trials in South Korea / NCT07476157
Starting soon Phase 1

A Study to Evaluate the Safety and Pharmacokinetics of AD-118 and AD-1181 in Healthy Adult Subjects

NCT07476157 · tracked via the Priya Life Science South Korea tracker
Sponsor
Addpharma Inc
Phase
Phase 1
Started
2026-04
Last updated
2026-03-17

Condition(s) studied

Chronic Heart Failure

Investigational drug(s) / intervention(s)

AD-118, AD-1181 →

AD-118, AD-1181: Single-dose oral administration of AD-118 or AD-1181, according to randomized sequence.

Study summary

A Study to Evaluate the Safety and Pharmacokinetics of AD-118 and AD-1181 Under Fasted Conditions in Healthy Adult Subjects

Eligibility

Sex
ALL
Min age
19 Years
Max age
64 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Body weight equal to or greater than 50kg and Body mass index (BMI) between 18.0 kg/m2 and 30.0 kg/m2 at the time of screening visit * Subjects aged 19 years or older and under 65 years at the screening visit Exclusion Criteria: * Participation in another clinical study with an investigational drug within the 6 months from scheduled first administration * Other exclusions applied

Primary outcome measure(s)

  • Area under the plasma concentration-time curve during dosing interval (AUCt) — pre-dose (0hour) to 36hours
    AUCt of AD-118
  • Maximum concentration of drug in plasma (Cmax) — pre-dose (0hour) to 36hours
    Cmax of AD-118

Trial sites (1)

FacilityCityRegionStatus
H PLUS YANGJI HOSPITAL, Seoul Seoul South Korea

More Addpharma Inc. trials in South Korea

Evaluate the Pharmacokinetic Interaction and the Safety of AD-2321 and AD-2322 Starting soon
A Clinical Trial to Assess the Pharmacokinetics, Safety, and Food Effect of AD-230 in Healthy Adults Starting soon
A Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-231A and AD-231B and AD-231C Starting soon
A Clinical Trial to Evaluate the Bioequivalence of AD-116A and AD-1161 Under Fed Conditions in Healthy Adult Male Volunteers Starting soon
A Study to Evaluate the Safety and Pharmacokinetics of AD-231 Compared to Coadministration of AD-231A, AD-231D and AD-231C Starting soon

Other trials for the same condition

A Study to Learn More About How Safe Finerenone is and How Well it Works in Adults With Chronic Heart Failure in South Korea Recruiting
A Study to Evaluate the Safety, Pharmacokinetics of AD-118 and AD-1181 in Healthy Adult Subjects Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07476157 on ClinicalTrials.gov ↗ ← All trials in South Korea