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Clinical Trials in South Korea / NCT07440940
Recruiting Not applicable

Timing of Subcostal TAPB Combined With Rectus Sheath Block for Postoperative Pain After Laparoscopic Cholecystectomy

NCT07440940 · tracked via the Priya Life Science South Korea tracker
Sponsor
Eulji University Hospital
Phase
Not applicable
Started
2026-02-23
Last updated
2026-02-27

Condition(s) studied

Postoperative PainLaparoscopic Cholecystectomy

Investigational drug(s) / intervention(s)

Ultrasound-guided subcostal TAP block combined with rectus sheath block

Ultrasound-guided subcostal TAP block combined with rectus sheath block: Ultrasound-guided right subcostal transversus abdominis plane (TAP) block combined with bilateral rectus sheath block (RSB) is performed under sterile conditions using local anesthetic for postoperative analgesia.

Study summary

This prospective randomized controlled trial aims to evaluate whether the timing of ultrasound-guided subcostal transversus abdominis plane (TAP) block combined with rectus sheath block (RSB) affects postoperative pain in patients undergoing laparoscopic cholecystectomy.

Participants will be randomly assigned to receive the combined regional blocks either before surgical incision or after completion of surgery. The primary outcome is postoperative pain intensity measured using a numerical rating scale. Secondary outcomes include opioid consumption, incidence of postoperative nausea and vomiting, and other recovery parameters.

The results of this study may help optimize the timing of abdominal wall blocks to improve postoperative analgesia and recovery following laparoscopic cholecystectomy.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * Elective laparoscopic cholecystectomy * Adults aged 18 to 80 years * Ability to understand the study procedures and provide informed consent * American Society of Anesthesiologists (ASA) physical status I-III Exclusion Criteria: * Presence of significant pain unrelated to the target disease that may interfere with pain assessment * Known allergy or contraindication to study medications (ropivacaine, acetaminophen, nefopam, or pethidine) * Planned single-port laparoscopic cholecystectomy * American Society of Anesthesiologists (ASA) physical status IV or higher * Infection of the abdominal wall or skin at the injection site, or anatomical abnormalities of the abdominal wall * Major neurological, psychiatric, or systemic diseases that may affect pain perception, treatment response, or study evaluation * Requirement for postoperative mechanical ventilation * Pregnancy or breastfeeding * Considered unsuitable for the study by the investigator * Refusal to participate or inability to provide informed consent

Primary outcome measure(s)

  • Maximum postoperative pain intensity within 24 hours — Within 24 hours after surgery
    The highest postoperative pain intensity measured using an 11-point numeric rating scale (NRS; 0 = no pain, 10 = worst pain imaginable) during the first 24 hours after surgery, assessed at 1, 6, 12, and 24 hours postoperatively.

Trial sites (1)

FacilityCityRegionStatus
Nowon Eulji University Hospital Seoul South Korea Recruiting

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Other trials for the same condition

Comparison of the Postoperative Analgesic Effects of the Temperature-responsive Gel Mixed With Local Anesthetics Application and Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Gastrectomy Starting soon
Efficacy of Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen After Cesarean Section Recruiting
Analgesia Nociception Index in Orthognathic Surgery Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07440940 on ClinicalTrials.gov ↗ ← All trials in South Korea