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Clinical Trials in Poland / NCT06920849
Active, not recruiting Not applicable

Evaluation of the Influence of PRF (Platelet-rich Fibrin) on the Clinical Parameters and the Concentration of Selected Inflammation Mediators in GCF (Gingival Crevice Fluid) of Patients With Periodontitis

NCT06920849 · tracked via the Priya Life Science Poland tracker
Sponsor
Medical University of Bialystok
Phase
Not applicable
Started
2022-04-01
Last updated
2025-04-10

Condition(s) studied

Periodontal DiseasePeriodontitis

Investigational drug(s) / intervention(s)

SRP+iPRF →SRP

SRP+iPRF: SRP (scaling and root planing) with iPRF (injectable platelet-rich fibrin)

SRP: SRP (scaling and root planing)

Study summary

Assessment of the influence of injectable platelet-rich fibrin (i-PRF) on the clinical parameters and the inflammation mediators levels in the gingival crevicular fluid (GCF) in patients with periodontitis.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * clinical and radiological features of periodontitis in stage II, III or IV * presence of at least 4 teeth and at least 2 pockets (localized not on the same tooth) with a depth of at least 5 mm in each quadrant Exclusion Criteria: * periodontal treatment within 3 months prior to the study; * antibiotic therapy within 3 months prior to the study; * smoking; presence of systemic diseases affecting periodontal healing, i.e.: immunosuppressive diseases, diabetes, osteoporosis, AIDS, hypertension treated with calcium channel blockers; * use of steroids or other immunosuppressive drugs; * coagulation disorders and use of drugs affecting its mechanisms; * pregnant and breastfeeding women

Primary outcome measure(s)

  • Assessment of the influence of injectable platelet-rich fibrin on the clinical parameters in non-surgical treatment of periodontitis. — up to 6 months after treatment procedure
    PD (Pocket Depth) from the gingival margin to the bottom of the sulcus, measured in mm

Trial sites (1)

FacilityCityRegionStatus
Department of Integrated Dentistry, Medical University of Białystok Bialystok Poland

More Medical University of Bialystok trials in Poland

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Other trials for the same condition

The Influence of Local Antibiotic Therapy on the Outcomes Following Periodontal Regeneration Procedures. Active, not recruiting
Evaluation Of The Efficacy Of Subgingival Application Of Lovastatin Gel As An Adjunct To Non-Surgical Treatment Of Periodontitis In Generally Healthy Smokers And Non-Smokers Patients in Central Europe. Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06920849 on ClinicalTrials.gov ↗ ← All trials in Poland