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Trackers› Clinical trials› Arnhem
Clinical trial register · Netherlands

Clinical Trials in Arnhem, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Netherlands and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 3203 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:48 UTC
3203
Studies in scope
all four open statuses
1832
Recruiting now
open to new participants
608
Lead sponsors
across recruiting studies
Top sites
Amsterdam 1240 Rotterdam 867 Groningen 601 Nijmegen 559 Utrecht 541
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Recruitment status
Phase
Lead sponsor
Radboud University Medical Center16 Rijnstate Hospital12 Stichting Hemato-Oncologie voor Volwassenen Nederland11 AstraZeneca8 The Netherlands Cancer Institute6
Site location
Amsterdam1240 Rotterdam867 Groningen601 Nijmegen559 Utrecht541
All 161 locations
Target enrolment
to

Trials with a site in Arnhem

187 of 3203 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Netherlands
Start
Not yet open
A Physical Activity Programme Focussed on Step Volume and Intensity for People With Cardiovascular Disease: Getting Active and Staying Active After Cardiac Rehabilitation
NCT07723274Coronary Artery Disease
Radboud University Medical Center
Not applicable
334
Arnhem, Nijmegen, Uden
2026-09-01
Recruiting
Radiotherapy Dose Escalation for Non-operative Management of Unresectable Locally Recurrent Rectal Cancer (STEP-UP)
NCT07721181Locally Recurrent Rectal Cancer
Heike M.U. Peulen
Not applicable
30
Arnhem, Eindhoven, Rotterdam, Utrecht
2026-09-01
Recruiting
ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3
NCT06716021Atrial Fibrillation
Milestone Pharmaceuticals Inc.
Phase 3
750
Arnhem, Roosendaal, Alkmaar, Almelo, Rotterdam, Friesland
2026-08-20
Recruiting
Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial)
NCT07582458Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Chronic Fatigue
DrugModafinil
Radboud University Medical Center
Phase 2/3
60
Arnhem, Nijmegen
2026-08-03
Recruiting
Individual Patient Data Meta-Analysis of Prospective Studies of Patients Treated With the GORE® Iliac Branched Endoprosthesis
NCT07704671Aneurysm
Rijnstate Hospital
Observational
1,200
Arnhem
2026-07-31
Recruiting
Promoting Response to IMmunotherapy by Exercise in Patients With Advanced Renal Cell Carcinoma
NCT07680556Oncology
Radboud University Medical Center
Not applicable
30
Arnhem, Nijmegen
2026-07-22
Recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
NCT07564414Obesity, Type 2 Diabetes
DrugsCagriSema·Semaglutide
Novo Nordisk A/S
Phase 3
2,500
Born, 's-Hertogenbosch, Arnhem, Eindhoven, Hoofddorp, Hoogeveen, Rotterdam, The Hague
2026-05-21
Recruiting
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
NCT07517263Cardiovascular Disease and Lipoprotein(a)
DrugPelacarsen
Novartis Pharmaceuticals
Phase 3
5,700
Apeldoorn, Arnhem, Tiel, Heerlen, Tilburg, Alkmaar, Amsterdam, Heemstede
2026-05-11
Active, closed
AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss
NCT07503210Obesity
DrugNNC0487-0111
Novo Nordisk A/S
Phase 3
606
Born, 's-Hertogenbosch, Almere Stad, Amersfoort, Arnhem
2026-04-21
Not yet open
Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity
NCT07504172Overweight , Obesity, Obesity (Disorder)
DrugTirzepatide
Radboud University Medical Center
Observational
1,700
Amsterdam, Arnhem, Beverwijk, Gouda, Heerlen, Hoogeveen, Nieuwegein, Terneuzen
2026-04-01
Not yet open
CRYO-1: Cryoablation in Elderly Patients With Early-Stage Breast Cancer.
NCT07398118Breast Cancer Stage I, Breast Cancer Early Stage Breast Cancer (Stage 1-3)
St. Antonius Hospital
Not applicable
61
Arnhem, Breda, Amsterdam
2026-04-01
Not yet open
SVF-Treo Study: Influence of Cardiac and Respiratory Pulsatility Deformation
NCT07475260Abdominal Aortic Aneurysm, Endovascular Abdominal Aortic Aneurysm Repair, Fenestrated Endovascular Aortic Repair
University of Twente
Observational
25
Arnhem, 's-Hertogenbosch, Amsterdam, Enschede, Utrecht, Heerlen
2026-04-01
Recruiting
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
NCT07556887Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
Maastricht University Medical Center
Not applicable
613
Arnhem, Nijmegen, Heerlen, Maastricht, Amsterdam, Zwolle, Dordrecht, Rotterdam
2026-03-31
Recruiting
Impact of Aorto-Iliac Occlusive Disease Treatment on Blood Pressure
NCT07070583Aorto Iliac Occlusive Disease, Blood Pressure
Rijnstate Hospital
Not applicable
20
Arnhem
2026-03-30
Recruiting
Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)
NCT07223814Acute Myeloid Leukemia
DrugsBleximenib·Idarubicin·Daunorubicin·Cytarabine
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
875
Amersfoort, Amsterdam, Arnhem, Breda, Dordrecht, Eindhoven, Groningen, Leeuwarden
2026-03-01
Recruiting
Stimulus Equivalence Learning in Acquired Brain Injury.
NCT07345481Acquired Brain Injury (Including Stroke)
Klimmendaal Revalidatiespecialisten
Observational
40
Arnhem
2026-01-29
Recruiting
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
NCT07063745Metastatic Non-small Cell Lung Cancer With MTAP Deletion
DrugsBMS-986504·Nab-paclitaxel·Pemetrexed·Paclitaxel
Bristol-Myers Squibb
Phase 2/3
590
Heerlen, Veldhoven, Arnhem, Groningen
2026-01-02
Recruiting
Chemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated With Adjuvant Ribociclib
NCT07237256Breast Cancer
UNICANCER
Phase 3
3,902
Arnhem, Hilversum, Hoofddorp, Leeuwarden, Leiden, Venlo
2025-12-18
Recruiting
Study for Frail Patients With Newly Diagnosed Multiple Myeloma Treated With Daratumumab With Teclistamab or Talquetamab.
NCT07107529Multiple Myeloma (MM)
DrugsTalquetamab·Teclistamab·Daratumumab
European Myeloma Network B.V.
Phase 2
150
Amsterdam, Arnhem, Enschede, Groningen, Nieuwegein, Schiedam, Sittard, The Hague
2025-12-12
Recruiting
Open and Closed Loop DTM SCS in Patients With PSPS Type 2: ENDLESS Study
NCT07211308Persistent Spinal Pain Syndrome Type 2, Failed Back Surgery Syndrome, Failed Neck Surgery Syndrome
Universitair Ziekenhuis Brussel
Observational
200
Arnhem, Nijmegen
2025-12-12
Active, closed
A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome
NCT07219602Lipidemia, Type 2 Diabetes (T2DM), Metabolic Syndrome (MetS)
DrugsEzetimibe FDC·Obicetrapib
NewAmsterdam Pharma
Phase 3
300
Hoogeveen, Arnhem, Alkmaar, Deventer, Zwijndrecht
2025-12-11
Recruiting
Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy
NCT07304401Chemotherapy Induced Peripheral Neuropathy (CIPN), Neuropathic Pain
Rijnstate Hospital
Observational
20
Arnhem, Nieuwegein, Roosendaal, Tilburg, Zwijndrecht
2025-12-01
Recruiting
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
NCT07241390Atherosclerosis Cardiovascular Disease, Chronic Kidney Disease
DrugOrforglipron
Eli Lilly and Company
Phase 3
7,140
's-Hertogenbosch, Almere Stad, Amersfoort, Amsterdam, Apeldoorn, Arnhem, Dirksland, Doetinchem
2025-12-01
Recruiting
NO Re-excision MelanomA - NORMA 2
NCT07530887Melanoma (Skin Cancer)
Marieke Goodijk
Phase 3
1,749
's-Hertogenbosch, Alkmaar, Almere Stad, Amsterdam, Apeldoorn, Arnhem, Eindhoven, Enschede
2025-11-13
Recruiting
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
NCT07225504Secondary Progressive Multiple Sclerosis (SPMS)
DrugRemibrutinib
Novartis Pharmaceuticals
Phase 3
1,275
Arnhem, 's-Hertogenbosch, Amsterdam, Leiden
2025-11-11
Recruiting
The TASTY-training Study
NCT07258589Oncological Patients, Tyrosine Kinase Inhibitor
University Medical Center Groningen
Not applicable
90
Amsterdam, Arnhem, Dirksland, Ede, Groningen, Nijmegen, Rotterdam, Scheemda
2025-11-10
Recruiting
Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs
NCT07309848Blood Transfusion, Hip Fracture Surgeries, Geriatric, Bleeding Complications
St. Antonius Hospital
Observational
374
Almelo, Amsterdam, Arnhem, Deventer, Groningen, Utrecht
2025-11-01
Recruiting
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
NCT07217067Atrial Fibrillation
Novartis Pharmaceuticals
Phase 2
165
Arnhem, Maastricht, Delft, Goes, Groningen, Veldhoven
2025-10-28
Recruiting
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
NCT06793215Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
DrugsDivarasib·Pemetrexed·Cisplatin·Carboplatin
Hoffmann-La Roche
Phase 3
600
Amersfoort, Amsterdam, Arnhem, Breda, Harderwijk, Leidschendam, Zwolle
2025-10-24
Recruiting
Individualised Endometrial Cancer Risk Stratification by Bayesian Prediction Model (ENDORISK), Optimizing Clinical Implementation
NCT07200466Endometrial Cancer
Radboud University Medical Center
Not applicable
735
Arnhem, Doetinchem, Ede, Nijmegen, Winterswijk, 's-Hertogenbosch, Breda, Eindhoven
2025-10-23
Recruiting
Clinical Phase 2 Trial of AP31969 Versus Placebo for Rhythm Control of Atrial Fibrillation
NCT07267949Atrial Fibrillation (AF)
Acesion Pharma
Phase 2
200
Arnhem, Deventer, Groningen, Haarlem, Leeuwarden, Maastricht, The Hague, Tiel
2025-10-22
Recruiting
#AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial.
NCT06900829HIV Infection, HIV, Stigma, Education
Casper Rokx
Not applicable
5,200
Arnhem, Eindhoven, Groningen, Rotterdam, The Hague
2025-10-01
Recruiting
Shorter Weaning From Invasive Ventilation With Levosimendan
NCT07105202Mechanical Ventilation, Weaning Failure
DrugLevosimendan
Radboud University Medical Center
Phase 4
250
Arnhem, Nijmegen, 's-Hertogenbosch, Eindhoven, Rotterdam
2025-09-17
Recruiting
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
NCT07157774Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)
Eli Lilly and Company
Phase 3
10,450
Alkmaar, Almere Stad, Amersfoort, Amsterdam, Arnhem, Born, Ede, Hilversum
2025-09-02
Recruiting
Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy
NCT07075016Acute Myeloid Leukemia
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
227
's-Hertogenbosch, Amsterdam, Arnhem, Breda, Dordrecht, Eindhoven, Enschede, Geleen
2025-08-05
Recruiting
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
NCT07037433Atherosclerotic Cardiovascular Disease, Overweight, Obesity
DrugMaridebart cafraglutide
Amgen
Phase 3
12,800
Alkmaar, Almelo, Almere Stad, Amersfoort, Amstelveen, Amsterdam, Apeldoorn, Arnhem
2025-07-25
Recruiting
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
DrugsVicadrostat·Dapagliflozin
Boehringer Ingelheim
Phase 3
11,800
's-Hertogenbosch, Amersfoort, Amsterdam, Arnhem, Beverwijk, Born, Delft, Eindhoven
2025-07-22
Recruiting
[18F]F-FAPI PET/CT and Laparoscopy in Staging Advanced Gastric Cancer
NCT07018661Locally Advanced Gastric Adenocarcinoma, STOMACH NEOPLASM, Gastric Cancer, PET-CT
Leiden University Medical Center
Phase 2/3
250
Almelo, Amsterdam, Arnhem, Eindhoven, Geleen, Groningen, Leiden, Rotterdam
2025-07-03
Recruiting
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
NCT07037459Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction, Obesity
DrugMaridebart cafraglutide
Amgen
Phase 3
5,056
Amsterdam, Arnhem, Breda, Delft, Deventer, Dordrecht, Eindhoven, Emmen
2025-06-25
Recruiting
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
NCT06943872Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
DrugsSonrotoclax·Venclexta·Obinutuzumab·Venetoclax
BeOne Medicines
Phase 3
630
Almere Stad, Arnhem, Dordrecht, Hilversum
2025-06-11
Recruiting
The TASTY-steering Study
NCT07258563Metastatic Triple Negative Breast Cancer, Metastatic Testicular Cancer, Stage II-IV Diffuse Large B Cell Lymphoma
University Medical Center Groningen
Not applicable
201
Amsterdam, Arnhem, Dirksland, Ede, Groningen, Nijmegen, Rotterdam, Scheemda
2025-06-06
Recruiting
Sequential Imaging of Suspicion of Prostate Cancer Reducing Overdiagnosis and Unnecessary Biopsy With Timely Diagnosis of Significant Cancer
NCT07180381Prostate Cancer
St. Antonius Hospital
Not applicable
503
Emmen, Arnhem, Nijmegen, Amsterdam, Rotterdam, Nieuwegein
2025-05-14
Recruiting
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
NCT06652438Acute Myeloid Leukemia, Adult
DrugRevumenib
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
448
's-Hertogenbosch, Amersfoort, Amsterdam, Arnhem, Breda, Delft, Dordrecht, Eindhoven
2025-05-05
Recruiting
OPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal Tumor-infiltrating Lymphocytes
NCT06476119Breast Cancer Stage I, Triple Negative Breast Cancer (TNBC)
The Netherlands Cancer Institute
Observational
490
Sittard-Geleen, Enschede, Alkmaar, Almere Stad, Amersfoort, Amsterdam, Arnhem, Breda
2025-04-15
Recruiting
Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation-2 (TELSTAR-2)
NCT06549426Coma, Electrographic Status Epilepticus
University of Twente
Not applicable
150
Amsterdam, Arnhem, Breda, Eindhoven, Enschede, Groningen, Leiden, Nieuwegein
2025-04-10
Recruiting
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
NCT06819878Moderately to Severely Active Crohns Disease
DrugAfimkibart
Hoffmann-La Roche
Phase 3
600
Arnhem, Sittard-Geleen, Tilburg, Utrecht
2025-03-17
Recruiting
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
NCT06841354Triple Negative Breast Neoplasms
DrugsSacituzumab tirumotecan·Nab-paclitaxel·Gemcitabine·Paclitaxel
Merck Sharp & Dohme LLC
Phase 3
1,000
Arnhem, Sittard Geleen, Tilburg, Deventer, Rotterdam, Amersfoort, Groningen
2025-03-16
Recruiting
Safety and Efficacy of Intravenous Thrombolysis in Patients With Ischemic Stroke and Direct Oral Anticoagulants Intake
NCT06571149Ischemic Stroke
DrugsAlteplase·Tenecteplase
Insel Gruppe AG, University Hospital Bern
Phase 4
906
Amsterdam, Arnhem, Breda, Dordrecht, Eindhoven, Groningen, Leiden, Maastricht
2025-03-14
Recruiting
A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)
NCT06833073Urinary Bladder Neoplasms, Non-Muscle Invasive Bladder Neoplasms, Carcinoma in Situ
DrugIntismeran autogene
Merck Sharp & Dohme LLC
Phase 2
308
Arnhem, Rotterdam
2025-03-11
Recruiting
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
NCT06764875HER2-positive Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
DrugsRilvegostomig·Trastuzumab deruxtecan·Adrucil·Trastuzumab
AstraZeneca
Phase 3
840
Amsterdam, Arnhem, Leiden
2025-03-01
Recruiting
A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
NCT06646276Extensive-Stage Small Cell Lung Cancer
DrugsEtoposide·Atezolizumab·Nivolumab·Carboplatin
Bristol-Myers Squibb
Phase 3
530
Amsterdam, Arnhem, Groningen
2025-02-25
Recruiting
Placebo Effect In Spinal Cord Electrical Stimulation for Pain
NCT06585033Chronic Postoperative Pain
Sahlgrenska University Hospital
Not applicable
50
Arnhem
2024-11-15
Recruiting
The Effect of a 2-week Preoperative Vegan Diet Versus Omnivorous Diet on the Protein Turnover in the Osteoarthritic Knee
NCT06130956Osteo Arthritis Knee, Protein Synthesis
Wageningen University
Not applicable
40
Arnhem, Ede
2024-10-22
Recruiting
Remimazolam Versus Midazolam for Sedation During Upper GI Endoscopy: a Randomized Controlled Trial
NCT06614036Sedation for Diagnostic Gastroscopy
DrugsRemimazolam·Midazolam
Koen Munters
Phase 4
148
Apeldoorn, Arnhem, Nieuwegein
2024-10-21
Not yet open
Validating Digital Biomarkers to Detect Disease Activity and Disease Progression in Multiple Sclerosis
NCT06627465Multiple Sclerosis
Amsterdam UMC, location VUmc
Observational
600
Arnhem, Geleen, Amsterdam
2024-10-15
Recruiting
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
NCT06561386Non-small Cell Lung Cancer
DrugsRelatlimab·Pemetrexed·Nivolumab·Cisplatin
Bristol-Myers Squibb
Phase 3
1,000
Harderwijk, Heerlen, 's-Hertogenbosch, Zwolle, Leiden, The Hague, Arnhem, Groningen
2024-10-07
Recruiting
Pain in Endometriosis And the Relation to Lifestyle
NCT06332560Endometriosis, Adenomyosis
Radboud University Medical Center
Not applicable
250
's-Hertogenbosch, Arnhem, Breda, Eindhoven, Nijmegen
2024-10-04
Recruiting
Implementation of Home Monitoring in Patients With Pulmonary Fibrosis
NCT06883448Pulmonary Fibrosis, Interstitial Lung Disease (ILD)
Erasmus Medical Center
Not applicable
220
Amsterdam, Arnhem, Breda, Eindhoven, Heerlen, Leeuwarden, Leiden, Nieuwegein
2024-10-02
Active, closed
A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer
NCT06497556Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
DrugsDivarasib·Sotorasib·Adagrasib
Hoffmann-La Roche
Phase 3
338
's-Hertogenbosch, Arnhem, Breda, Harderwijk, Leidschendam, Zwolle
2024-09-23
Recruiting
Rehabilitation After a Hip Fracture: the Effects of Dietary Protein and Exercise on Bone and Muscle Health and Quality of Life
NCT07036341Hip Fractures
Wageningen University
Not applicable
102
Arnhem, Ede
2024-09-01
Active, closed
A Phase 2a/b Study of the Efficacy and Safety of Subcutaneous Amlitelimab in Adults With Nonresponsive Celiac Disease
NCT06557772Coeliac Disease, Celiac Disease
DrugAmlitelimab
Sanofi
Phase 2
229
Amsterdam, Arnhem
2024-08-29
Recruiting
Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma
NCT06220032DLBCL - Diffuse Large B Cell Lymphoma
DrugsDexrazoxane·Pegfilgrastim·Prednisolone·Vincristine
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
324
's-Hertogenbosch, Almelo, Amstelveen, Apeldoorn, Arnhem, Breda, Delft, Dordrecht
2024-08-15
Recruiting
Spinal Cord Monitoring in Multiple Sclerosis
NCT06827834Multiple Sclerosis
Zuyderland Medisch Centrum
Observational
155
Arnhem, Geleen, 's-Hertogenbosch, Dordrecht, Rotterdam
2024-08-06
Recruiting
LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
NCT06216301Metastatic Non-small Cell Lung Cancer
DrugPembrolizumab
NovoCure GmbH
Phase 3
734
Arnhem, Friesland, Harderwijk, Utrecht
2024-07-31
Recruiting
DUTCH Weight Control in Atrial Fibrillation Study
NCT06184633Atrial Fibrillation, Obesity, Weight Loss
DrugSemaglutide
Rijnstate Hospital
Phase 4
280
Arnhem
2024-07-21
Recruiting
DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer
NCT06275958Older Patients, Colorectal Cancer, Metastatic Cancer, Candidates for Palliative Chemotherapy
DrugReduced
Leiden University Medical Center
Phase 3
587
's-Hertogenbosch, Alkmaar, Amstelveen, Amsterdam, Arnhem, Assen, Beverwijk, Doetinchem
2024-07-01
Recruiting
Permissive Weight Bearing in Displaced Intra-articular Calcaneal Fractures
NCT05721378Calcaneus Fracture, Displaced Intra-Articular Fracture of Calcaneus (Diagnosis), Trauma Injury
Maastricht University Medical Center
Not applicable
115
Amsterdam, Arnhem, Breda, Eindhoven, Gouda, Maastricht, Nijmegen, Rotterdam
2024-07-01
Recruiting
Bariatric Surgery Evaluation and Assessment of Treatment Efficacy - Intervention Trial
NCT06065124Heart Failure with Preserved Ejection Fraction, Atrial Fibrillation
University Medical Center Groningen
Not applicable
108
Arnhem, Groningen
2024-07-01
Active, closed
ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
NCT06118281Cardiovascular Risk, Acute Myocardial Infarction (AMI)
DrugZiltivekimab
Novo Nordisk A/S
Phase 3
10,000
's-Hertogenbosch, Alkmaar, Amersfoort, Amsterdam, Arnhem, Breda, Eindhoven, Enschede
2024-06-25
Recruiting
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
NCT06424288Heart Failure
DrugsVicadrostat·Dapagliflozin
Boehringer Ingelheim
Phase 3
6,712
's-Hertogenbosch, Arnhem, Breda, Deventer, Eindhoven, Gouda, Leiderdorp, Nieuwegein
2024-06-17
By invitation
Reference Values for Gastric Emptying Scintigraphy After Bariatric Surgery
NCT06391255Gastric Emptying, Bariatric Surgery
Rijnstate Hospital
Observational
50
Arnhem
2024-05-29
Recruiting
FeAsiBility of a Treatment Free Interval in Newly Diagnosed MM Patients Treated With Daratumumab-lenalidomide-dexamethasone (HOVON174MM)
NCT06187441Multiple Myeloma
DrugsDaratumumab·Lenalidomide·Dexamethasone
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
599
's-Hertogenbosch, Almere Stad, Amersfoort, Amsterdam, Apeldoorn, Arnhem, Assen, Beverwijk
2024-05-14
Recruiting
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
NCT06312176Breast Neoplasms
DrugsLiposomal doxorubicin·Sacituzumab tirumotecan·Nab-paclitaxel·Capecitabine
Merck Sharp & Dohme LLC
Phase 3
1,200
Arnhem, Maastricht, Breda, Eindhoven, Amsterdam, Zwolle, Amersfoort
2024-04-14
Recruiting
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
NCT06307652Heart Failure and Impaired Kidney Function
AstraZeneca
Phase 3
3,850
Amsterdam, Arnhem, Emmen, Goes, Hardenberg, Leeuwarden
2024-04-12
Recruiting
Integrated Molecular and Clinical Profiling to Improve Disease Characterization and Outcome Prediction in Nodal Marginal Zone Lymphoma
NCT05700149Nodal Marginal Zone Lymphoma
International Extranodal Lymphoma Study Group (IELSG)
Observational
300
Arnhem
2024-04-11
Active, closed
AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion
NCT06029660Aortic Aneurysm, Abdominal
Shape Memory Medical, Inc.
Not applicable
180
Arnhem, Tilburg, Amsterdam, Rotterdam
2024-04-05
Recruiting
Prospective, Non-Randomised Clinical Trial to Investigate the BeGraft Aortic Stent Graft System and the BeGraft Peripheral Stent Graft System Treating Aortic-iliac Occlusive Disease
NCT05805111Aorto-iliac Occlusive Disease
Marc Bosiers, MD
Observational
109
Alkmaar, Arnhem, Groningen, Maastricht, The Hague
2024-04-05
Recruiting
Early Cessation of Sedation and TTM in Patients With a Favourable EEG After Cardiac Arrest
NCT06048796Hypoxia-Ischemia, Brain, Heart Arrest
Medisch Spectrum Twente
Not applicable
40
Arnhem, Enschede
2024-03-12
Recruiting
Omentum Preservation Versus Complete Omentectomy in Gastrectomy for Gastric Cancer
NCT05180864Stomach Neoplasm
Amsterdam UMC
Not applicable
654
Amsterdam, Almelo, Apeldoorn, Arnhem, Eindhoven, Groningen, Heerlen, Leeuwarden
2024-03-01
Active, closed
Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab
NCT06237920Urologic Neoplasms, Urogenital Neoplasms, Neoplasms by Site, Neoplasms
DrugsRelatlimab·Opdivo·Nivolumab
The Netherlands Cancer Institute
Phase 2
90
Arnhem, Nijmegen, Amsterdam, Hoofddorp, Zwolle, Leiden, Rotterdam, Utrecht
2024-02-19
Active, closed
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
NCT06191744Follicular Lymphoma (FL)
DrugsEpcoritamab·Bendamustine·Obinutuzumab·Vincristine
Genmab
Phase 3
1,095
Roosendaal, Tilburg, Amsterdam, Leiden, Rotterdam, The Hague, Nieuwegein, Arnhem
2024-02-05
Recruiting
A Trial to Assess Cobicistat Boosted Venetoclax in Combination With Azacitidine in Adult Patients With Newly Diagnosed AML
NCT06014489AML, Adult
DrugsCobicistat·Azacitidine·Venetoclax
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 2
142
's-Hertogenbosch, Amersfoort, Amsterdam, Arnhem, Breda, Dordrecht, Eindhoven, Enschede
2024-01-17
Recruiting
Enhancing Successful Return to Work of Employees With Cancer, by Supporting Employers (MiLES Intervention)
NCT06672887Cancer, Neoplasm
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Phase 2/3
140
Arnhem, Dordrecht, Hengelo, Utrecht, Zeeland
2023-12-18
Recruiting
Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)
NCT05512364ER-positive Breast Cancer, HER2-negative Breast Cancer, Stage IIB Breast Cancer, Stage III Breast Cancer
DrugsElacestrant·Tamoxifen·Exemestane·Anastrozole
European Organisation for Research and Treatment of Cancer - EORTC
Phase 3
220
Almere Stad, Amsterdam, Arnhem, Leidschendam, Rotterdam, Utrecht, Venlo
2023-12-15
Recruiting
Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm
NCT05779631Bladder Cancer, Muscle-invasive Bladder Cancer
Radboud University Medical Center
Not applicable
360
's-Hertogenbosch, Almelo, Amersfoort, Amsterdam, Arnhem, Boxmeer, Ede, Emmen
2023-12-06
Recruiting
Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.
NCT05333523Laryngeal Squamous Cell Carcinoma, Hypopharynx Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma
Radboud University Medical Center
Phase 3
242
Amsterdam, Arnhem, Enschede, Groningen, Leiden, Maastricht, Nijmegen, Rotterdam
2023-12-06
Recruiting
Rewards for Cannabis Abstinence-study
NCT05836207Cannabis Use Disorder
Parnassia Addiction Research Centre
Not applicable
154
Amsterdam, Arnhem, Rotterdam, The Hague, Vught
2023-11-21
Recruiting
Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)
NCT06095583Limited-stage Small Cell Lung Cancer (LS-SCLC)
DrugToripalimab
Shanghai Junshi Bioscience Co., Ltd.
Phase 3
756
's-Hertogenbosch, Arnhem, Rotterdam, Zwolle
2023-11-15
Recruiting
The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease
NCT05811364Aortoiliac Occlusive Disease, Peripheral Arterial Disease
W.L.Gore & Associates
Not applicable
244
Arnhem, Tilburg
2023-10-17
Active, closed
Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2
NCT05911295Urothelial Carcinoma
DrugsDisitamab Vedotin·Gemcitabine·Cisplatin·Carboplatin
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
412
Amsterdam, Arnhem, Breda, Nijmegen, The Hague
2023-09-22
Recruiting
The Course and Outcome of Integreated Trauma and Addiction Treatment Between PTSD and CPTSD
NCT06588309PTSD, Addiction
IrisZorg
Observational
50
Arnhem
2023-09-01
Active, closed
Tislelizumab, Gemcitabine and Cisplatin for R/R Hodgkin Lymphoma Followed by Tislelizumab Consolidation in Patients in Metabolic Complete Remission
NCT05502250Hodgkin Lymphoma
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 2
75
Amersfoort, Amsterdam, Arnhem, Eindhoven, Goes, Groningen, Hoofddorp, Leeuwarden
2023-07-14
Active, closed
Safety of Ticagrelor Monotherapy After Primary Percutaneous Coronary Intervention for ST-elevation Myocardial Infarction and the Effect on Intramyocardial Haemorrhage
NCT05986968ST Elevation Myocardial Infarction
DrugsTicagrelor·Aspirin
Radboud University Medical Center
Not applicable
200
Alkmaar, Amsterdam, Arnhem, Enschede, Nijmegen
2023-07-06
Active, closed
ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
NCT05671510Non Small Cell Lung Cancer
DrugsGotistobart·Taxotere·Docetaxel
OncoC4, Inc.
Phase 3
630
Amsterdam, Arnhem, Tilburg
2023-06-28
Recruiting
Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients
NCT05701241Gastroenteropancreatic Neuroendocrine Tumor
DrugsOctreotide·Lanreotide
University Hospital, Antwerp
Phase 4
270
Arnhem, Maastricht, Eindhoven, Amsterdam, Groningen, Rotterdam
2023-06-28
Recruiting
An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.
NCT05907057Acute Myeloid Leukemia (AML)
DrugsIvosidenib·Azacitidine
Servier Affaires Médicales
Phase 3
245
Amersfoort, Amsterdam, Arnhem, Groningen
2023-06-14
Recruiting
Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck
NCT05484115Aortic Aneurysm, Abdominal
Rijnstate Hospital
Not applicable
300
Alkmaar, Haarlem, Arnhem, Eindhoven
2023-05-26
Active, closed
Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients
NCT05705973Cardiovascular Disease, Coronary Artery Occlusion, Ischemic Heart Disease
Terumo Europe N.V.
Observational
3,000
's-Hertogenbosch, Arnhem, Dordrecht, Eindhoven, Leeuwarden, Rotterdam
2023-04-25
Recruiting
COntinue the SaMe Systemic Therapy After Local Ablative Therapy for Oligo Progression in Metastatic Breast Cancer - the COSMO Study
NCT05301881Breast Cancer Invasive, Metastatic Cancer, Oligoprogressive
The Netherlands Cancer Institute
Phase 2
56
Alkmaar, Amsterdam, Arnhem, Deventer, Goes, Groningen, Utrecht
2023-04-17
Active, closed
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
NCT05739383Primary Prevention of Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals
Phase 3
14,012
Arnhem, Doetinchem, Nijmegen, 's-Hertogenbosch, Tilburg, Amsterdam, Beverwijk, Deventer
2023-03-09
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Dutch investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 26 September 2026. https://priyalifescience.com/clinical-trials-netherlands/city/arnhem

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Netherlands and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 3,203 studies in total at the last sync on 26 Sep 2026, 19:48 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 187 of those studies with a site in Arnhem.

How many clinical trials are recruiting in Arnhem?

108 of the 187 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:48 UTC sync. A further 5 have not yet opened recruitment, 68 are active but closed to new participants, and 6 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Arnhem), 187 studies
PhaseStudiesRecruitingShare
Phase 3733739%
Observational411921.9%
Not applicable403021.4%
Phase 219910.2%
Phase 41095.3%
Phase 2/3442.1%

Most active sponsors

Lead sponsors with the most studies (Arnhem)
Lead sponsorStudiesRecruiting
Radboud University Medical Center1611
Rijnstate Hospital126
Stichting Hemato-Oncologie voor Volwassenen Nederland117
AstraZeneca82
The Netherlands Cancer Institute63
University Medical Center Groningen64
Merck Sharp & Dohme LLC53
Leiden University Medical Center42
Maastricht University Medical Center44
Novartis Pharmaceuticals43
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.