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Clinical Trials in the Netherlands / NCT07345481
Recruiting Observational

Stimulus Equivalence Learning in Acquired Brain Injury.

NCT07345481 · tracked via the Priya Life Science Netherlands tracker
Sponsor
Klimmendaal Revalidatiespecialisten
Phase
Observational
Started
2026-01-29
Last updated
2026-05-22

Condition(s) studied

Acquired Brain Injury (Including Stroke)

Study summary

Stimulus Equivalence Learning (SEL) is a form of learning in which stimuli (such as words, pictures, or sounds) become linked to one another in memory, even though this specific connection has not been directly taught. In a typical SEL task, two relations are taught explicitly (A→B and A→C), and the untrained relation (B→C) is then tested. This indirect relation is not intentionally or consciously learned and is considered a form of implicit learning. The principle of stimulus equivalence learning is still rarely applied in cognitive rehabilitation after acquired brain injury (ABI), with the exception of a few small (N=1) treatment studies that have shown positive effects. However, it remains unclear to what extent ABI may affect the ability to acquire stimulus equivalence.

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
Accepted
Inclusion Criteria: ABI patients (\>3 months post-injury), including stroke, traumatic brain injury, brain tumor, encephalitis, and out-of-hospital cardiac arrest (OHCA). Exclusion Criteria: Neurodegenerative disorders Severe psychiatric disorders (including suicidality) Insufficient command of the Dutch language Severe cognitive impairments, aphasia, or visual or hearing problems that make test administration impossible An additional exclusion criterion for controls was any medical condition that could lead to cognitive impairment beyond normal aging, including stroke, TBI, brain tumor, or other forms of brain injury.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Klimmendaal Revalidatiespecialisten Arnhem Gelderland Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07345481 on ClinicalTrials.gov ↗ ← All trials in the Netherlands