Functional MRI During Resting State in Patients with Eating Disorders

Condition(s) studied

Investigational drug(s) / intervention(s)

structural and functional MRI: structural and functional MRI

Study summary

The goal of this observational study is to learn if clinical and neurophysiological characteristics dynamics may follow similar trends in a longitudinal characterization of patients with a diagnosis of an eating disorder.

The primary hypothesis is that the reversal of Functional Magnetic Resonance Imaging (fMRI) baseline alternations is positively associated with symptomatic amelioration.

The secondary hypothesis is that the degree of (f)MRI baseline alternations is positively associated with symptoms.

Participants will be asked to complete psychometric questionnaires, perform a fMRI and be recalled at 12 months for a follow-up.

Eligibility

Primary outcome measure(s)

• Change in cortical thickness — baseline, 12 months post-enrollment
• Weight restoration — baseline - 12 months post-enrollment
• Child Behavior Checklist (CBCL) score — Baseline - 12 months post enrollment
• Children's Depression Inventory (CDI) score — baseline, 12 months post-enrollment
• Multidimensional Anxiety Scale for Children (MASC) — Baseline - 12 months post-enrollment
• Eating Disorder Inventory (EDI) psychometric score — Baseline - 12 months post-enrollment

Trial sites (2)

More Meyer Children's Hospital IRCCS trials in Italy

Other trials for the same condition