Alveolar Ridge Preservation: Biologically-oriented Alveolar Ridge Preservation Vs Modified Periosteal Inhibition
Condition(s) studied
Investigational drug(s) / intervention(s)
BARP: deep layers of collagen, medium-superficial heterologous bone graft, superficial collagen layer
Modified Periosteal Inhibition Technique: Cortical lamina stabilized with human fibrin glue to preserve the buccal wall of the socket. The socket was then filled with collagen.
Study summary
The modified periosteal inhibition technique has been proposed as an alternative to limit crestal resorption following tooth extraction in sockets with a residual vestibular thickness of \<1 mm. This technique aims to prevent osteolytic activity on the external surface of a post-extraction socket by applying a 0.5 mm-thick soft cortical plate of porcine origin, secured with fibrin glue. By avoiding the placement of bone graft material inside the socket, the technique seeks to effectively counteract bone remodeling, achieving minimal reduction in the size of the alveolar crest.
The aim is to evaluate the effectiveness of the modified periosteal inhibition technique in preserving the dimensions of the alveolar ridge after tooth extraction, by comparing it with the Biologically-oriented Alveolar Ridge Preservation technique.
Eligibility
Primary outcome measure(s)
- ridge width reduction — 26 weeks after tooth extraction and preservation tecnhique
optical scanning comparison measured in millimetres at the mid-buccal and mid-palatal aspect of the socket - ridge height reduction — 26 weeks after tooth extraction and preservation tecnhique
optical scanning comparison measured in millimetres at the mid-buccal, mid-palatal, mesial and distal aspect of the socket
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| University of Trieste | Trieste | TS |
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06784232 on ClinicalTrials.gov ↗ ← All trials in Italy