Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide
Clinical Trials in Italy / NCT06546826
Active, not recruiting Observational

Alveolar Ridge Preservation After Tooth Extraction

NCT06546826 · tracked via the Priya Life Science Italy tracker
Sponsor
International Piezosurgery Academy
Phase
Observational
Started
2024-01-06
Last updated
2025-07-31

Condition(s) studied

Alveolar Bone Loss

Investigational drug(s) / intervention(s)

BARPsimple tooth extractiontooth root and PRFIce cream cone technique

BARP: deep layers of collagen, medium-superficial heterologous bone graft, superficial collagen layer

simple tooth extraction: tooth extraction without grafting procedure.

tooth root and PRF: Autogenous roots derived from the extracted hopeless tooth and stabilized with osteosynthesis screws to reconstruct the missing buccal wall of the socket. The defect was then filled with PRF.

Ice cream cone technique: xenogeneic granules and a resorbable collagen membrane

Study summary

Post-extractive alveolar ridge remodeling represents a physiological phenomenon that may hamper successive implant insertion. Several techniques have been proposed without any significant difference of efficacy among them. Moreover several research protocols of analysis have been proposed, including histomorphometric, radiological, clinical analysis.

The purpose of the present study is to test different alveolar ridge preservation techniques using histomorphometric and optical scanning analysis.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Age between 18 and 80 years; * Single-rooted tooth with indication for extraction and presenting adjacent teeth; * Presence of type II defect; * Sufficient bone height of the extraction site for the insertion of a standard implant (≥8.5 mm); * Healthy oral mucosa with at least 3 mm of keratinized tissue; * American Society of Anesthesiologists 3; * Periodontal health or stability; * Signature of informed consent. Exclusion Criteria: * Presence of general contraindications for oral surgery; * Presence of inflammatory and autoimmune diseases; * Uncontrolled diabetes (HbA1c 7%); * History of tumors requiring chemotherapy or radiotherapy in the last 5 years; * Previous therapy with bisphosphonates or high-dose corticosteroid therapy; * Smoking (10 cigarettes/day); * Allergy to bovine collagen; * Pregnancy or breastfeeding; * Lack of compliance.

Primary outcome measure(s)

  • alveolar volume — 6 months post-extractive
    optical scanning comparison

Trial sites (1)

FacilityCityRegionStatus
University of Trieste, Departmen of Medicine, Surgery, Health Sciences Trieste Trieste

More International Piezosurgery Academy trials in Italy

Effect Of Cavitation In Post-Extractive Socket Healing Recruiting
Alveolar Ridge Preservation: Biologically-oriented Alveolar Ridge Preservation Vs Modified Periosteal Inhibition Active, not recruiting
Influence of Implant Insertion Torque on Post-Surgical Marginal Bone Stability Active, not recruiting
Clinical Influence of Different Surface Treatments on Implant Stabiity Recruiting
Use of Radiomics in the Evaluation of Bone Quality After Alveolar Ridge Preservation Enrolling by invitation

Other trials for the same condition

Alveolar Ridge Preservation: Biologically-oriented Alveolar Ridge Preservation Vs Modified Periosteal Inhibition Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06546826 on ClinicalTrials.gov ↗ ← All trials in Italy