Clinical Trials in Italy / NCT06718920
Recruiting
Observational
Adverse Childhood Experiences in Patients With MS: Impact on Quality of Life and on Coping Strategies Towards the Disease and Its Treatment
NCT06718920 · tracked via the Priya Life Science Italy tracker
Condition(s) studied
Multiple Sclerosis
Study summary
The goal of this observational study is to evaluate the presence of adverse childhood experiences (ACE) in patients with Multiple Sclerosis. The main questions it aims to answer are:
* Does the presence of ACE impact on quality of life of patients with multiple sclerosis?
* Does it influence how the patients cope with the disease and with disease course-modifying therapies? During follow up visits, planned as part of their regular medical care, participants will answer survey questions on a tablet .
Eligibility
Inclusion Criteria:
* Age older than 18 years;
* Diagnosis of relapsing-remitting multiple sclerosis according to McDonald criteria (2017 revisions) made between 2014 and 2024.
* Signature of informed consent
Exclusion Criteria:
* Presence of language barrier
* Presence of conditions that prevent or limit understanding and proper completion of questionnaires
Primary outcome measure(s)
- To assess the prevalence of ACE in a cohort of patients with relapsing-remitting multiple sclerosis — At enrollement
The patients will answer to questionnaires provided on an electronic tablet during regular follow up neurological visits. The presence of adverse childhood experiences will be explored through the completion of a specific questionnaire: Childhood Trauma Questionnaire (CTQ): score 0-28 Higher scores mean higher probability to have experienced ACE - To assess the prevalence of ACE in a cohort of patients with relapsing-remitting multiple sclerosis — At enrollement
The patients will answer to questionnaires provided on an electronic tablet during regular follow up neurological visits. The presence of dysfunctional parenting during childhood will be explored through the completion of the Measure of Parental Style (MOPS) questionnaire (score 0-28): higher scores mean higher probability to have experienced dysfunctional parenting, leading to ACE
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Rome | RM | Recruiting |
More Fondazione Policlinico Universitario Agostino Gemelli IRCCS trials in Italy
Modular Neurological Examination for Early Risk Detection
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Other trials for the same condition
A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis
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Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis
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Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06718920 on ClinicalTrials.gov ↗ ← All trials in Italy