A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Condition(s) studied
Investigational drug(s) / intervention(s)
IMVT-1402: Dose 1 for 26 weeks
IMVT-1402: Dose 2 for 26 weeks
Placebo: For 26 weeks
Study summary
This is a multi-center, global, randomized, double-blind, placebo-controlled Phase 2b study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.
Eligibility
Primary outcome measure(s)
- Percentage of participants who are euthyroid and off ATD at Week 26 (Dose 1) — Week 26
Trial sites (163)
| Facility | City | Region | Status |
|---|---|---|---|
| Site Number - 1015 | Tucson | Arizona | Recruiting |
| Site Number -1014 | Concord | California | Recruiting |
| Site Number - 1013 | Aurora | Colorado | Recruiting |
| Site Number - 1024 | Doral | Florida | Recruiting |
| Site Number - 1008 | Hialeah | Florida | Recruiting |
| Site Number - 1000 | Miami | Florida | Recruiting |
| Site Number - 1020 | Columbus | Georgia | Recruiting |
| Site Number - 1022 | Topeka | Kansas | Recruiting |
| Site Number - 1030 | Louisville | Kentucky | Recruiting |
| Site Number - 1033 | Jefferson City | Missouri | Recruiting |
| Site Number - 1004 | Kansas City | Missouri | Recruiting |
| Site Number - 1019 | St Louis | Missouri | Recruiting |
| Site Number - 1012 | Reno | Nevada | Recruiting |
| Site Number - 1032 | Long Island City | New York | Recruiting |
| Site Number - 1027 | New Hyde Park | New York | Recruiting |
| Site Number - 1009 | New York | New York | Recruiting |
| Site Number - 1018 | Williamsville | New York | Recruiting |
| Site Number - 1010 | Chapel Hill | North Carolina | Recruiting |
| Site Number - 1026 | Hickory | North Carolina | Recruiting |
| Site Number - 1001 | Morehead City | North Carolina | Recruiting |
| Site Number - 1034 | Raleigh | North Carolina | Recruiting |
| Site Number - 1007 | Oklahoma City | Oklahoma | Recruiting |
| Site Number - 1017 | Memphis | Tennessee | Recruiting |
| Site Number - 1029 | Dallas | Texas | Recruiting |
| Site Number - 1002 | El Paso | Texas | Recruiting |
| Site Number - 1003 | Fort Worth | Texas | Recruiting |
| Site Number - 1031 | Houston | Texas | Recruiting |
| Site Number - 1028 | Houston | Texas | Recruiting |
| Site Number -1023 | Irving | Texas | Recruiting |
| Site Number - 1021 | Irving | Texas | Recruiting |
| Site Number - 1025 | McKinney | Texas | Recruiting |
| Site Number - 1011 | San Antonio | Texas | Recruiting |
| Site Number - 1016 | Norfolk | Virginia | Recruiting |
| Site Number - 5105 | Sydney | New South Wales | Recruiting |
| Site Number - 5103 | Warrawong | New South Wales | Recruiting |
| Site Number - 5101 | Brisbane | Queensland | Recruiting |
| Site Number - 5107 | Douglas | Queensland | Recruiting |
| Site Number - 5100 | Southport | Queensland | Recruiting |
| Site Number - 5102 | Box Hill | Victoria | Recruiting |
| Site Number - 5104 | Geelong | Victoria | Recruiting |
+ 123 more sites — see the full list on the official registry below.
More Immunovant Sciences GmbH trials in Israel
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07018323 on ClinicalTrials.gov ↗ ← All trials in Israel