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Clinical Trials in India / NCT07049965
Active, not recruiting Not applicable

Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy

NCT07049965 · tracked via the Priya Life Science India tracker
Sponsor
GSVM Medical College
Phase
Not applicable
Started
2024-04-01
Last updated
2025-07-03

Condition(s) studied

Appendicitis

Investigational drug(s) / intervention(s)

Suture ligationHarmonic Scalpel

Suture ligation: Participants will undergo laparoscopic appendectomy in which the base of the appendix is ligated using intracorporeal suturing with absorbable material. This is the conventional technique used to prevent stump leakage.

Harmonic Scalpel: Participants will undergo laparoscopic appendectomy where the base of the appendix is sealed and divided using the harmonic scalpel. This ultrasonic energy-based device cuts and coagulates tissue simultaneously, potentially reducing operative time and blood loss.

Study summary

This study is a comparative study between use of suture ligation vs harmonic scalpel for sealing and cutting the base of appendix.

The ideal method for closing the appendix stump should be safe, reliable, simple to use, and cost-effective. Various techniques have been introduced for this purpose, each with its advantages and disadvantages. However, no clear consensus has been reached in the literature regarding which technique is superior.

This study is to compare the two groups in terms of operative time and postoperative complications and to reach a conclusion as to which one of the two is superior.

Eligibility

Sex
ALL
Min age
5 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: 1. 5 - 65 years 2. Any gender 3. Patient willing to undergo laparoscopic appendectomy 4. Acute appendicitis confirmed by clinical and radiological analysis 5. Alvarado Score ≥7 6. Alvarado Score ≥5 with positive ultrasound findings Exclusion Criteria: 1. Patient with base of appendix highly inflamed / gangrenous 2. Any other intra-abdominal pathology other than acute appendicitis, e.g., appendicular mass, appendicular abscess, tuberculosis, carcinoid tumor, pelvic inflammatory disease, ovarian tumors, ceacal mass, etc. 3. Patients declared unfit for laparoscopic surgery during preoperative assessment 4. Patients having severe co morbid condition - COPD/CAD/CHF

Primary outcome measure(s)

  • Operative time — Intraoperative( measured during surgical procedure on day 1)
    Total duration of surgery in minutes, measured from skin incision to completion of appendix base closure. Used to compare efficiency between harmonic scalpel and suture ligation techniques.

Trial sites (1)

FacilityCityRegionStatus
Ganesh Shankar Vidhyarthi Memorial Medical College Kanpur Kanpur Uttar Pradesh

More GSVM Medical College trials in India

Comparison Between Laser and Open Fistula Surgeries in the Management of Fistula - In - Ano Active, not recruiting
A Comparative Study Between TAPP and Lichtenstein Techniques for Inguinal Hernia Surgery Active, not recruiting

Other trials for the same condition

A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07049965 on ClinicalTrials.gov ↗ ← All trials in India