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Clinical Trials in India / NCT06643663
Recruiting Not applicable

Role of GTR on Healing Outcome & Quality of Life in Combined Endo Perio Lesions With Communication

NCT06643663 · tracked via the Priya Life Science India tracker
Sponsor
Postgraduate Institute of Dental Sciences Rohtak
Phase
Not applicable
Started
2024-05-23
Last updated
2025-01-08

Condition(s) studied

Periapical DiseasesEndodontic Disease

Investigational drug(s) / intervention(s)

Endodontic Micro-Surgery

Endodontic Micro-Surgery: Surgery performed using ACM membrane and PRF plug in test group \& without membrane \& PRF in control group.

Study summary

The recovery of periapical defects linked to periodontal communication frequently yields less satisfactory results. Numerous studies and case reports have highlighted the notable success achieved through the application of guided tissue regeneration techniques. More recently, autologous platelet concentrate plug \& placental membrane have emerged as a treatment option for addressing such lesions. Nevertheless, there has been no study using PRF-Medium with ACM membrane on the healing of aforesaid lesion \& quality of life assessment.

Eligibility

Sex
ALL
Min age
16 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: 1. Patients of age 16yrs and above. 2. Patients with apico-marginal defects and deep pocket upto apex of tooth. 3. Failed primary root canal treatment. 4. Presence of interproximal bone loss. 5. Negative response to vitality test. 6. ASA-1 or ASA- 2 according to the classification of the American Society of Anesthesiologists) Exclusion criteria: 1. Presence of vertical root fracture 2. Presence of root perforations 3. ASA-3 or ASA-4 according to the classification of the American Society of Anesthesiologists) 4. Presence of root resorption 5. Combined endodontic-periodontic lesions. 6. Pregnancy

Primary outcome measure(s)

  • Periapical healing assessment — Base line to 12 months
    Periapical healing comparison in 2 groups 2D radiographic healing by Rud et al and Molven et al criteria and 3D healing by modified PENN 3D Criteria. Healing will be categorised into complete, incomplete, uncertain, unsaisfactory.

Trial sites (1)

FacilityCityRegionStatus
Pgids Rohtak Haryāna India Recruiting

More Postgraduate Institute of Dental Sciences Rohtak trials in India

a Prospective Randomised Study Evaluating the Efficacy of Intranasal Midazolam and Dexmedetomidine as a Sedative Agent in Management of Mandible Fracture Enrolling by invitation
TO DETERMINE THE EFFECT OF ALLOGRAFT AND iPRF WITH OR WITHOUT COLLAGEN MEMBRANE ON HEALING OF APICOMARGINAL DEFECTS Recruiting
Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars Recruiting
Motivational Interviewing and Subgingival Instrumentation Outcomes in Periodontitis Starting soon
Comparative Evaluation of Periodontal Status and Periodontal Parameters in Different Age Group Individuals With and Without Trauma From Occlusion. Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06643663 on ClinicalTrials.gov ↗ ← All trials in India