Cognitive Enhancement in Unipolar Depression With Yoga

Condition(s) studied

Investigational drug(s) / intervention(s)

Adjuvant yoga intervention: The yoga will include following asanas under the supervision of a yoga therapist. This will include Griva Shithilikarana, Skandha Sanchalana , Kati Sanchalana, Jaanu Sanchalana, Pada Sanchalana, Tadasana, Kati Sakti Vikasaka, Konasana,Marjari Asana, Vakrasana, Pascimottanasana, Matsyasana, Bhujangasana, Ardha Shalabhasana, Viparitakarani, Pavanamuktasana, Setubhandasana, Shavasana, Kapalabhati, Surya-anuloma pranayama, Chandraanuloma pranayama, Bhastrika, Bhramari Pranayama, Nadanusandhana.

Study summary

It is evident from recent studies that cognitive deficits persist even after remission of depressive episode. Hence, in this study, the investigators would like to see whether specific Yoga practice will help in enhancing cognitive abilities in this population.

Eligibility

Primary outcome measure(s)

• Working memory (Digit Span) — Baseline, after six weeks yoga and after four weeks of completion of yoga
  To study the change in working memory in intervention group as measured by digit span test in comparison to treatment as usual. The range of the scale is 0 to 28 points and higher is better memory.
• Attention and processing speed(Trail A and B) — Baseline, after six weeks yoga and after four weeks of completion of yoga
  To study the change in attention and processing speed in intervention group as measured by Trail A and B test in comparison to treatment as usual. The scoring is based on time taken to complete the test. Less the time taken, better the attention and processing speed.
• Cognitive flexibility — Baseline,after six weeks yoga and after four weeks of completion of yoga
  To study the change in cognitive flexibility in intervention group as measured by stroop test test in comparison to treatment as usual. Stroop test also measures time to complete the task and less the time, better the score is.
• Cognitive inhibition — Baseline,after six weeks yoga and after four weeks of completion of yoga
  To study the change in cognitive inhibition in intervention group as measured by stroop test test in comparison to treatment as usual.

Trial sites (1)