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Clinical Trials in India / NCT06472492
Recruiting Not applicable

Cognitive Enhancement in Unipolar Depression With Yoga

NCT06472492 · tracked via the Priya Life Science India tracker
Sponsor
University of Pittsburgh
Phase
Not applicable
Started
2024-05-17
Last updated
2026-03-27

Condition(s) studied

Unipolar Depression

Investigational drug(s) / intervention(s)

Adjuvant yoga intervention

Adjuvant yoga intervention: The yoga will include following asanas under the supervision of a yoga therapist. This will include Griva Shithilikarana, Skandha Sanchalana , Kati Sanchalana, Jaanu Sanchalana, Pada Sanchalana, Tadasana, Kati Sakti Vikasaka, Konasana,Marjari Asana, Vakrasana, Pascimottanasana, Matsyasana, Bhujangasana, Ardha Shalabhasana, Viparitakarani, Pavanamuktasana, Setubhandasana, Shavasana, Kapalabhati, Surya-anuloma pranayama, Chandraanuloma pranayama, Bhastrika, Bhramari Pranayama, Nadanusandhana.

Study summary

It is evident from recent studies that cognitive deficits persist even after remission of depressive episode. Hence, in this study, the investigators would like to see whether specific Yoga practice will help in enhancing cognitive abilities in this population.

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * Age more than 18years and less than 60 years * H/o at least one depressive episode which is under remission and at the time of examination and throughout the study duration, * Informed Consent Exclusion Criteria: * Comorbid Psychosis, OCD, Bipolar disorder * Comorbid ADHD, IDD * Comorbid substance dependence (except tobacco) * Comorbid major or minor cognitive impairment, * Bi temporal ECT within 6 months * Past yoga practice - regularly for 1 month within 3 months Pregnancy

Primary outcome measure(s)

  • Working memory (Digit Span) — Baseline, after six weeks yoga and after four weeks of completion of yoga
    To study the change in working memory in intervention group as measured by digit span test in comparison to treatment as usual. The range of the scale is 0 to 28 points and higher is better memory.
  • Attention and processing speed(Trail A and B) — Baseline, after six weeks yoga and after four weeks of completion of yoga
    To study the change in attention and processing speed in intervention group as measured by Trail A and B test in comparison to treatment as usual. The scoring is based on time taken to complete the test. Less the time taken, better the attention and processing speed.
  • Cognitive flexibility — Baseline,after six weeks yoga and after four weeks of completion of yoga
    To study the change in cognitive flexibility in intervention group as measured by stroop test test in comparison to treatment as usual. Stroop test also measures time to complete the task and less the time, better the score is.
  • Cognitive inhibition — Baseline,after six weeks yoga and after four weeks of completion of yoga
    To study the change in cognitive inhibition in intervention group as measured by stroop test test in comparison to treatment as usual.

Trial sites (1)

FacilityCityRegionStatus
National Institute of Mental Health and Neuroscience (NIMHANS) Bengaluru Karnataka Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06472492 on ClinicalTrials.gov ↗ ← All trials in India