Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact
Recruiting Not applicable

Comparison Between Objective Biomechanical Cost and Perceived Physical Demand in Manual Wheelchair Users During Propulsion Tasks

NCT07897214 · tracked via the Priya Life Science France tracker
Phase
Not applicable
Started
2026-10-19
Last updated
2026-10-27

Condition(s) studied

Manual Wheelchair UseSpinal Cord Injury

Investigational drug(s) / intervention(s)

Instrumented Manual Wheelchair Propulsion Tasks (Motion Analysis and Instrumented Handrims)Concurrent Cognitive Task (Auditory-Verbal 2-back)

Instrumented Manual Wheelchair Propulsion Tasks (Motion Analysis and Instrumented Handrims): Participants perform standardized manual wheelchair propulsion tasks (straight-line propulsion, propulsion with a concurrent cognitive dual task, propulsion on a ramp, on varied floor surfaces, with turns, and along a path with an object to reach) while equipped with reflective motion-capture markers and using wheels instrumented with 6-axis force sensors on the handrim, in order to estimate biomechanical loading at the shoulder and relate it to subjective measures of perceived demand.

Concurrent Cognitive Task (Auditory-Verbal 2-back): An auditory-verbal 2-back task is added concurrently to a propulsion task (dual task) to examine the effect of cognitive load on propulsion technique and on cognitive performance, compared to single-task propulsion.

Study summary

Wheelchair users must be able to move around freely and access public buildings and transport, but current accessibility standards (e.g. maximum 8% ramp slope) are based on limited scientific evidence about the real biomechanical and perceived difficulties encountered by manual wheelchair users in daily life.

Manual wheelchair propulsion is not purely a motor activity: it also involves cognitive and emotional demands (attention, trajectory planning, stress and frustration management) that contribute to a mental workload. This cognitive dimension is still rarely integrated into biomechanical evaluation protocols.

This exploratory (pilot) study aims to test the feasibility of a protocol combining objective biomechanical data (shoulder joint loading estimated from motion capture and instrumented handrims) with the subjective experience of participants (perceived physical demand from the NASA-TLX questionnaire, perceived exertion from the Borg scale), during standardized and more realistic manual wheelchair propulsion tasks, including tasks performed under an added cognitive load (auditory-verbal 2-back dual task).

Eligibility

Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: * Adult participant over 18 years of age * Person having signed the informed consent form * Duration of manual wheelchair use prior to the experiment greater than 2 weeks * Ability to perform transfers autonomously, with or without a technical aid * Functional criterion: patient who uses the wheelchair autonomously during the day Non-inclusion Criteria: * Refusal of the person to participate or to sign the consent form * Diagnosed cognitive disorder * Upper limb amputation * Refusal of the person to propel the wheelchair bimanually * Upper limb injury * Average upper limb pain over the past two weeks, on a 0 (no pain) to 10 scale: \< 4 * Person aged over 70 years

Primary outcome measure(s)

  • Correlation Between Perceived Physical Demand (NASA-TLX) and Objective Biomechanical Shoulder Load — During the experimental session (Day 1)
    Spearman correlation between the physical demand subscore of the NASA-TLX questionnaire and the biomechanical cost estimated at the shoulder (kinematic and kinetic parameters derived from motion capture and instrumented handrim force data, using an upper-limb biomechanical model), during simple and more physically demanding propulsion tasks (ramp, floor surface change).

Trial sites (1)

FacilityCityRegionStatus
Centre Médico-Chirurgical de Réadaptation des Massues Lyon France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07897214 on ClinicalTrials.gov ↗ ← All trials in France