Study of General Foetal Movements Using Ultrasound

Condition(s) studied

Investigational drug(s) / intervention(s)

External or endovaginal ultrasound: Endovaginal or external ultrasound specifically for research at 13, 17 (if amniocentesis), 23 and 33 weeks of amenorrhoea (+/- 10 days) (on average 10% endovaginal / 90% external ultrasound). Each patient will undergo one to four additional ultrasound scans.

Study summary

This research explores General Movements (GMs) in a reference population. Abnormal general movements in babies are predictive of autism spectrum disorders or neurodevelopmental deficits.

General movements have received little attention in the context of foetuses, which is why developing a reading grid to analyse general movements in foetuses could be a valuable tool for facilitating early diagnosis and prompt treatment of at-risk babies.

Eligibility

Primary outcome measure(s)

• Quantitative and Qualitative Parameters of General Fetal Movements Assessed by Ultrasound Recordings Across Gestation — 9 months
  Presence, frequency, and characteristics of abnormal fetal movement patterns identified on ultrasound recordings obtained at 13, 17, 23, and 33 weeks of amenorrhea (±10 days). Recordings will be independently assessed by experts in fetal ultrasonography and General Movements Assessment using the General Movements Assessment grid adapted for preterm infants. Reported outcomes will include the occurrence and type of abnormal movement patterns at each assessment time point.

Trial sites (1)

Other trials for the same condition