Active, not recruiting
Not applicable
Effect of an Antioxidant Dietary Supplement on Skin Radiance
Condition(s) studied
Healthy Women
Investigational drug(s) / intervention(s)
Antioxidant SupplementPlacebo
Antioxidant Supplement: Oral antioxidant dietary supplement administered as one capsule once daily for 90 days.
Placebo: Placebo dietary supplement administered as one capsule once daily for 90 days.
Study summary
A randomized, double-blind, placebo-controlled study evaluating the effects of an oral antioxidant dietary supplement on skin radiance in women exposed to urban air pollution. Secondary assessments include skin tone homogeneity, pigmentation, inflammation, skin barrier function, glycation markers.
Eligibility
Inclusion Criteria:
* Healthy female subjects aged 35 to 65 years.
* Fitzpatrick skin phototype II to IV.
* Any skin type.
* Dull and uneven skin complexion.
* Living in an urban environment and exposed to pollution.
* No change in hormonal treatment within the past 3 months.
* Able to understand the study procedures and provide informed consent.
* Willing and able to comply with study requirements.
* Written informed consent obtained.
* Covered by health insurance.
* Willing to avoid unprotected sun exposure and use SPF 50 sunscreen throughout the study.
Exclusion Criteria:
* Pregnant or breastfeeding women, or women planning to become pregnant during the study.
* Current use of dietary supplements or vitamin supplements.
* Participation in another clinical trial involving a cosmetic product, drug, or medical device.
* Use of oral or injectable corticosteroids within the past 3 months.
* Current treatment with immunosuppressive agents, chemotherapy, or radiotherapy.
* History of autoimmune disease or connective tissue disorder.
* Presence of an active dermatological condition that could affect study assessments.
* Following a vegetarian, vegan, or weight-loss diet.
* Not covered by health insurance.
* Participation in another clinical study during the exclusion period.
* Individuals considered vulnerable according to applicable regulations.
Primary outcome measure(s)
- Skin Radiance — Day 0 and Day 90
Glossymeter
Trial sites (1)
| Facility | City | Region | Status |
| Gredeco |
Paris |
France |
|
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