Ireland
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Recruiting Observational

Peripersonal Space Representation in Upper Limb Segmental Exclusion

NCT07349173 · tracked via the Priya Life Science France tracker
Phase
Observational
Started
2025-12-04
Last updated
2026-03-16

Condition(s) studied

Segmental Exclusion SyndromeComplex Regional Pain Syndrome (CRPS)Upper Limb Neglect (Peripheral)

Investigational drug(s) / intervention(s)

Reachability Judgment Task in VR.

Reachability Judgment Task in VR.: Participants wear an Oculus Quest 2 VR headset. They first perform a motor task to measure Real Reachable Distance (DMA-r). Then, they perform a perceptual task where they must judge, without moving, if a virtual object is reachable (DMA-p). The test evaluates different spatial planes (front, 45° right, 45° left) and heights (shoulder, navel).

Study summary

This study aims to evaluate the representation of action peripersonal space (PPS) in subjects suffering from unilateral segmental exclusion syndrome of the upper limb compared to healthy control subjects. Segmental exclusion is defined by non-use or under-use of a limb segment without central nervous system damage. The study hypothesizes that this syndrome leads to a modification (shrinkage) of the PPS representation. Participants will perform reachability judgments in a Virtual Reality (VR) environment.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria (patients): * Age ≥ 18 years. * Presenting unilateral exclusion symptom of the upper limb or part of the hand evolving for \> 3 months. * No contraindication to force work in daily activities. * For patients with finger exclusion: at least 2 perturbed items related to exclusion on tests 3 and 4 of the "Bilan 400 points". * Affiliated to a social security scheme. * Able to understand simple orders. Inclusion Criteria (Controls): * Age ≥ 18 years. * No history of upper limb impairment with sequelae. Exclusion Criteria (All): * Visual impairments. * Central neurological pathology. * Unstabilized psychiatric pathology. * Communication or comprehension difficulties. * Under legal protection or unable to consent. * Pregnant or breastfeeding women. * Cervical pathology contraindicating VR headset use. * Epilepsy. * Upper limb pathology unrelated to exclusion. * Inability to stand for 40 minutes.

Primary outcome measure(s)

  • Judgment Error of Reachability — Day 1 (During the 40-minute VR assessment)
    The Judgment Error of Reachability is a single composite metric calculated as: ((DMA-p - DMA-r) / DMA-r) × 100, expressed as a percentage (%). Both DMA-p (Perceived Maximum Reachable Distance) and DMA-r (Real Maximum Reachable Distance) are measured in centimeters, and their ratio yields a single dimensionless percentage score.

Trial sites (1)

FacilityCityRegionStatus
Institut Régional de Médecine Physique et de Réadaptation (IRR), Centre Louis Pierquin. Nancy France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07349173 on ClinicalTrials.gov ↗ ← All trials in France