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Clinical Trials in France / NCT06320288
Recruiting Observational

Analysis of Trunk and Center of Mass Control Development During Gait in Children With Cerebral Palsy (VERTEBRAL)

NCT06320288 · tracked via the Priya Life Science France tracker
Sponsor
Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Phase
Observational
Started
2023-09-20
Last updated
2026-01-12

Condition(s) studied

Children With Cerebral Palsy

Study summary

During the acquisition of posturokinetic abilities such as walking, postural control of the trunk is of paramount importance. Indeed, its development is strongly linked to the overall motor function of children. In cerebral palsy (CP), a term that refers to a set of motor disorders following a perinatal lesion, deficits in axial control are present from early childhood. These deficits are strongly correlated with the functional deficits observed in this population. In particular, during walking, deviations of the trunk (amplitudes, accelerations) are observed in the three planes of space. While recent literature increasingly questions the impact of trunk control deficit on the walking of children with CP, elements are still missing for a holistic understanding of the interaction between locomotor and postural disorders in children with CP. In particular, no study has focused on the deviations of trunk control and the center of mass (which is a global indicator of balance strategies) during the development and maturation of walking in children with CP. Therefore, the primary objective of this cross-sectional observational study will be to characterize the development of trunk control and center of mass during walking in children with CP.

Eligibility

Sex
ALL
Min age
18 Months
Max age
18 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Children (\< 18 years) with cerebral palsy * GMFCS I to III * Independent walking with or without technical walking aids (walker, crutches, etc.) * Able to understand the instructions of various clinical assessments and functional explorations * Affiliated with a social security scheme Exclusion Criteria: Children with cerebral palsy * Neuro-orthopaedic surgery of the lower limbs or trunk within the last 12 months * Botulinum toxin A injections within the last 6 months * Therapeutic intervention targeting trunk control last 6 months Typically developing children * Surgery on lower limbs or trunk last 12 months * Neurological and/or orthopedic pathology that may influence gait

Primary outcome measure(s)

  • Trunk and center-of-mass accelerations and acceleration variability — At the end of the one-day experimental
    In addition to the zeno walking track, inertial computers will be used to record accelerations of the patient's trunk and center of mass as they walk. One will be attached to the sternum, the other to the lumbosacral hinge, using hypoallergenic double-sided tape. A third will be attached to the patient's shoe to synchronize the data from the treadmill and the inertial units. Acceleration variability is calculated in post-processing.

Trial sites (1)

FacilityCityRegionStatus
Institut Régional de Médecine Physique et de Réadaptation Nancy France Recruiting

More Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est trials in France

Peripersonal Space Representation in Upper Limb Segmental Exclusion Recruiting
Trunk Activity Rehabilitation in Young Children With Cerebral Palsy Recruiting
Evaluation of the Effect of a Physical Activity Recovery Stay Recruiting
Clinical Evaluation of the Access Socket Flexible Socket for Transtibial Prosthesis Recruiting
Uses of Phantom Sensations Induced by Global and Local Modifications of the Prosthetic Socket as Somatosensory Feedback During Walking in Lower Limb Amputees Recruiting

Other trials for the same condition

Trunk Activity Rehabilitation in Young Children With Cerebral Palsy Recruiting
Evaluation of the Effect of a Physical Activity Recovery Stay Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06320288 on ClinicalTrials.gov ↗ ← All trials in France