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Clinical Trials in France / NCT07320040
Recruiting Observational

Evaluation of Emotion-related Salivary Molecular Biomarkers

NCT07320040 · tracked via the Priya Life Science France tracker
Sponsor
Sys2Diag
Phase
Observational
Started
2022-11-14
Last updated
2026-01-29

Condition(s) studied

Emotion

Investigational drug(s) / intervention(s)

Identication and measurement of a molecular biomarkers signature

Identication and measurement of a molecular biomarkers signature: Levels of the biomarkers of interest (DHEA, pg/mL; Oxytocin, pg/mL; Cortisol, pg/mL; Alpha Amylase, U/mL) will be measured in the saliva of participating subjects by enzymatic assay methods or ELISA-type methods performed using commercial kits.

Study summary

Recent studies show that emotional states can be discriminated by physiological responses. This physiological regulation results from the action of enzymes and hormones that represent the activity of the autonomic nervous system. The measurement of specific biomarkers, using non-invasive biological tests in saliva, would therefore provide physiological data on an individual's emotional state in response to stimuli, particularly olfactory stimuli.

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Subject willing to follow study procedures * Subject able to understand the purpose, nature and methodology of the study * Subject has signed informed consent form * Subjects between 18 and 60 years of age. Exclusion Criteria: * Subjects deprived of liberty, protected adults, vulnerable persons or minors * Subjects with a proven or suspected chronic infectious disease that could entail a risk of contamination during sample handling (laboratories not equipped to handle this type of sample) * Rejection to sign the consent form. Non specific inclusion criteria: * Pregnant or breastfeeding women * Subjects presenting anosmia during the last 15 days * Subjects presenting symptoms and signs of active oral inflammation, advanced periodontitis or severe gingivitis.

Primary outcome measure(s)

  • Evaluate variations — 1 year
    Evaluate variations in several molecular biomarkers in saliva following fragrance stimulus/stimuli that may be linked to an emotionnal response (positive or negative).

Trial sites (1)

FacilityCityRegionStatus
SYS2DIAG - UMR9005 CNRS/ALCEN, Montpellier, 34184 Montpellier France Recruiting

More Sys2Diag trials in France

Pilot Study on the Correlation Between Accelerations Experienced Recruiting
Salivary Biomarkers for Concussion Recruiting
Emotions From Salivary Biomarkers in an Architectural Context Starting soon
Evaluation of the Effect of Kefir Consumption Active, not recruiting

Other trials for the same condition

Effects of Virtual Reality With Multisensory Stimulation on Emotional and Behavioral Disorders in Individuals With Acquired Brain Injury and Disability Requiring Institutional Care: a Single Case Experimental Design (SCED) Study. Starting soon
Evaluation of the Effect of Kefir Consumption Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07320040 on ClinicalTrials.gov ↗ ← All trials in France