Imaging and Evolution of Pigmented Tumors of the Anterior Ocular System in Children

Condition(s) studied

Investigational drug(s) / intervention(s)

slit lamp examination: data collected: tumor size, pigmentation, vascularization, cells

dermatoscopy examination x20 and x400: data collected: tumor size, pigmentation, vascularization, cells

confocal microscopy examination: data collected: tumor size, pigmentation, vascularization, cells

Study summary

The investigators were interested in pigmented tumours of the anterior segment of the eye in children because there is very little data on their evolution. The nevus is the most common conjunctival tumour.

The challenge is to be able to adapt the child's follow-up according to the imaging and avoid an invasive procedure such as surgical excision if the imaging does not find any suspicious cells despite a change in size or colour. This would also make it possible to answer parents' questions about the potential evolution of the tumour. Finally, it would enable the frequency of monitoring to be personalised according to the data analysed. The tests are all non-invasive and painless.

Eligibility

Primary outcome measure(s)

• The size and pigmentation of the tumor — Day 1
  Measurement of the size of the tumor with dermatoscopy x20 in mm and pigmentation with the slit lamp as well as dermatoscopy x20 and x400

Trial sites (1)

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