European Registry of Acutely Decompensated Pulmonary Arterial Hypertension

Condition(s) studied

Study summary

Acute decompensation of pulmonary hypertension (PH) is associated with a very unfavorable short-term prognosis. However, the development of circulatory support techniques and the possible use of emergency transplantation in recent years has significantly changed the management of patients with refractory right ventricular failure. Nonetheless, there are significant disparities in the management of these patients depending on the organization of the care pathway, the rules for graft allocation, and access to circulatory support across European countries. Moreover, the implementation of these new therapeutic strategies requires the identification of effective prognostic factors and the development of new monitoring techniques. The objective of this collaborative clinical research project is to study the prognostic implications of acute decompensated right heart failure associated with PAH based on a large-scale European multicenter approach using a prospective analysis of clinical, biological, and echocardiographic data.

Eligibility

Primary outcome measure(s)

• 3-months mortality/lung transplantation — 3-months post inclusion
  3-months mortality/lung transplantation

Trial sites (1)

More Assistance Publique - Hôpitaux de Paris trials in France

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