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Clinical Trials in France / NCT06832436
Recruiting Observational

Atrial Strain in Septic Shock

NCT06832436 · tracked via the Priya Life Science France tracker
Sponsor
Centre Hospitalier Universitaire, Amiens
Phase
Observational
Started
2025-03-06
Last updated
2026-01-16

Condition(s) studied

Septic ShockLeft Atrial StrainRight Atrial StrainTransthoracic EchocardiographySpeckle TrackingEchocardiographic SoftwareReproducibilityCritical Care

Study summary

Septic shock is a critical condition associated with high mortality. Transthoracic echocardiography is widely used to evaluate cardiac function and guide treatment. Left and right atrial strain (LAS and RAS) measured via speckle tracking echocardiography have shown prognostic value in cardiovascular diseases. However, differences exist between echocardiographic software, leading to challenges in result comparability. This study aims to compare LAS and RAS measurements between ECHOPAC and UWS software, evaluate AutoStrain technology, and assess reproducibility across observers. The study is non-interventional and will use retrospective echocardiographic data from patients treated for septic shock. The findings will contribute to improving measurement standardization in critically ill patients.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age: \>18 years * Adult patients admitted to critical care for septic shock (SEPSIS-3 definition) * TTE performed as part of medical management * No objection to data usage Exclusion Criteria: * Pregnancy * Moderate to severe valvular regurgitation/stenosis (\>grade 2) * Ventricular or supraventricular tachyarrhythmia (HR \>140 bpm) at the time of TTE * Poor echogenicity preventing LAS measurement * Mechanical circulatory support * Pacemaker dependence * Patients under guardianship

Primary outcome measure(s)

  • variation of LASr between ECOPAC and UWS — 1 year
    Agreement of LAS Reservoir Phase (LASr) measurement in manual mode between ECHOPAC and UWS

Trial sites (1)

FacilityCityRegionStatus
CHRU Amiens Salouël France Recruiting

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Role of Candidate Proteins in Capillary Leakage During Acute Circulatory Failure Recruiting
Fluorescent Leukocytes as a Marker of Early Sepsis/Severity Starting soon
Rate, Rhythm or Risk Control for New-onset Supraventricular Arrhythmia During Septic Shock: a Randomized Controlled Trial Recruiting
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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06832436 on ClinicalTrials.gov ↗ ← All trials in France