Ireland
--:--IST
Recruiting Observational

Proof-of-concept Study on Dyspnea Analysis Via GapCO2

NCT06556797 · tracked via the Priya Life Science France tracker
Phase
Observational
Started
2025-01-26
Last updated
2026-02-10

Condition(s) studied

Acute DyspneaDyspnea

Study summary

Patients presenting to the emergency department with acute dyspnea undergo arterial blood gas measurement and monitoring of transcutaneous capnography using the TCM5 monitor. The aim of this study is to determine whether GapCO2, the difference between transcutaneous and arterial pCO2 (PaCO2 - PtcCO2), is correlated with the congestive or non-congestive origin of dyspnea.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age ≥ 18 years * Patient presenting with acute dyspnea defined by a sensation of respiratory discomfort with at least one of the following criteria: RR ≥ 22 and/or SpO2 \< 95% * Arterial blood gas sampling performed as part of care * Inclusion less than 1 hour after arrival time to the emergency department * Non-opposition to participation in the study Exclusion Criteria: * Temperature greater than or equal to 37.5°C * Patient who has already received a diuretic or vasodilator treatment in the emergency department or by a prehospital medical team * Systolic blood pressure less than or equal to 100 mmHg and/or signs of peripheral hypoperfusion * Inability to express refusal to participate in the study

Primary outcome measure(s)

  • GapCO2 — Within 1 hour after enrolment
    PaCO2 measured via arterial blood gas analysis - PtcCO2 measured via TCM5 monitor, at 37°C

Trial sites (1)

FacilityCityRegionStatus
Emergency Department Hospital Avicenne Bobigny France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06556797 on ClinicalTrials.gov ↗ ← All trials in France