Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide
Clinical Trials in France / NCT06528171
Recruiting Not applicable

Covid-19 Long Immunité IMagerie (CLIIM)

NCT06528171 · tracked via the Priya Life Science France tracker
Sponsor
Centre Hospitalier Universitaire de Nice
Phase
Not applicable
Started
2024-12-06
Last updated
2026-06-22

Condition(s) studied

COVID Long-Haul

Investigational drug(s) / intervention(s)

Brain MRISpecific blood samples

Brain MRI: non injected brain MRI

Specific blood samples: blood samples to find immunological and inflammatory markers

Study summary

Covid-long pathology affects a large number of patients, and represents a major medical, economic and societal challenge. To date, we have no objective criterion for a definitive diagnosis, nor any predictive tool for monitoring the evolution of Covid-long. Based on recruitment from the infectious diseases department of Nice University Hospital, the investigator's team wants to conduct an innovative pathophysiological study to better define the disease and identify specific biomarkers that could subsequently be used as a diagnostic tool for Covid-long. 120 participants will be initially included for the model learning phase: 60 controls in the CL- cohort and 60 patients in the CL+ cohort. Then 80 patients (40 CL+ and 40 Cl-) will be enrolled for the model validation phase.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
FOR CL+ PATIENTS Inclusion Criteria: * Case definition in line with WHO Delphi process Exclusion Criteria: * History of chronic fatigue syndrome diagnosed before or after Covid. * History of progressive psychiatric pathology. * History of acute Covid requiring admission to intensive care and mechanical ventilation. * No social security affiliation. FOR CONTROL (CL-) Inclusion Criteria: * History of acute COVID-19, mild, moderate or severe (episode at least 3 months at the time of inclusion). * Absence of persistent symptoms more than 3 months after first Covid symptoms (or mild not affecting daily activities). Exclusion Criteria: * History of progressive psychiatric pathology. * History of acute Covid requiring admission to intensive care and mechanical ventilation. * No social security affiliation. * Pregnant or breast-feeding.

Primary outcome measure(s)

  • Predictive model of Covid-long — 24 months
    Build and validate a multivariate predictive model of Covid-long considering immunological, inflammatory and brain imaging markers.

Trial sites (1)

FacilityCityRegionStatus
CHU de NICE Nice France Recruiting

More Centre Hospitalier Universitaire de Nice trials in France

Study of the Metabolism in the Lymphatic Niche of CLL Recruiting
Treatment and Prevention of Melasma Relapses by Using 1064nm 650 Microsecond Laser Active, not recruiting
The Benefits of Posterior Joint Infiltration in Chronic Low Back Pain Starting soon
Investigation of the Frequency of Hereditary Hyper Alpha-tryptasemia in Patients With Elevated Basal Tryptasemia Active, not recruiting
Multimodal Connectome Study of Brain Tumor-operated Patients Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06528171 on ClinicalTrials.gov ↗ ← All trials in France