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Recruiting Not applicable

Study of Intra- and Interpersonal Multimodal Synchronizations in a Social Interaction in Individuals with a Diagnosis of Schizophrenia.

NCT06484387 · tracked via the Priya Life Science France tracker
Phase
Not applicable
Started
2024-11-08
Last updated
2024-12-09

Condition(s) studied

Schizophrenia

Investigational drug(s) / intervention(s)

Social interaction

Social interaction: Participants are required to speak to one another. Participants are given various topics of conversation.

Study summary

The aim of this study is to precisely identify deficits in intra- and interpersonal multimodal synchronizations during social interaction in individuals with schizophrenia (ISZ). During a social interaction, individuals use both visual and auditory channels to construct their discourse. The auditory channel encompasses the semantics and prosody of the speech, while the visual channel describes the entirety of non-verbal gestures (e.g., facial expressions, body movements). Prosody and non-verbal gestures are essential elements for the speaker. By accompanying speech, they contribute to the planning and conceptualization of the utterance and enhance its communicative power. For the listener, prosody and non-verbal gestures are also used to provide sensory feedback to the speaker.

Several studies have shown the existence of intrapersonal and interpersonal synchronizations of prosody and non-verbal gestures during interaction. These synchronizations are associated with numerous social benefits (e.g., increased mutual appreciation and quality of interaction). However, certain mental disorders, such as schizophrenia, exhibit deficits in non-verbal behaviors that can impair these synchronizations and the associated social benefits. We hypothetized that interaction with individuals with a daignosis of schizophrenia will be associated with deficits in intra and interpersonal synchronization.

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
Accepted
Individuals with a diagnosis of schizophrenia : Inclusion Criteria: * diagnosis of schizophrenia according to the DSM-V * being able to read, speak and understand french * giving eclaired consent Exclusion Criteria: * history of head trauma * history of neurological conditions (epilespsy, multiple sclerosis, parkinson's disease, amyotrophic lateral sclerosis, huntington's disease, stroke) * substance use * pregnant women Healthy controls : Inclusion Criteria: * being able to read, speak and understand french * giving eclaired consent Exclusion Criteria: * diagnosis of psychosis * history of head trauma * history of neurological conditions (epilespsy, multiple sclerosis, parkinson's disease, amyotrophic lateral sclerosis, huntington's disease, stroke) * substance use * pregnant women

Primary outcome measure(s)

  • interpersonal synchronization — 4x6 minutes
    synchronization between body movements of two interacting partners
  • intrapersonal synchronization — 4x6 minutes
    synchronization between voice and body movements of one individual

Trial sites (1)

FacilityCityRegionStatus
Montpellier University Hospital Montpellier France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06484387 on ClinicalTrials.gov ↗ ← All trials in France