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Clinical Trials in France / NCT06130592
Recruiting Not applicable

Technical Feasibility Study of Ultrasound Muscle Imaging in Antenatal Ultrasound

NCT06130592 · tracked via the Priya Life Science France tracker
Sponsor
University Hospital, Grenoble
Phase
Not applicable
Started
2024-05-12
Last updated
2026-10-06

Condition(s) studied

Arthrogryposis Multiplex Congenita (AMC)

Investigational drug(s) / intervention(s)

ultrasound muscle imaging technique

ultrasound muscle imaging technique: ultrasound muscle imaging technique in antenatal ultrasound screening of congenital multiple arthrogryposis

Study summary

The objective of the study is to evaluate the performance of muscle ultrasound sections on antenatal ultrasound between 21-24 amenorrhea weeks for the screening of muscle atrophy, in a sample of low-risk and high-risk pregnancies of congenital multiple arthrogryposis

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
55 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Any pregnant woman consulting in one of the two obstetric gynecology departments in connection with the CPDPN (Multidisciplinary Prenatal Diagnostic Centers) of the University hospitals of Lyon or Grenoble. * Mono-embryonic pregnancy. * Gestational ages retained on the first dating ultrasound or the 1st trimester ultrasound between 21-24 amenorrhea weeks. * For women at "high risk": diagnosis during ultrasound of the 1st, 2nd, or 3rd trimesters, of an abnormality of position / deformation of one or more joints, and / or an abnormality of fetal movements on screening ultrasound or interrogation (population group at "high risk of AMC"). * Regulatory criteria: adults, affiliated to a social security scheme, having signed a consent Exclusion Criteria: * Multiple pregnancies, and / or non-progressive . * Obese women (BMI \> 30 in early pregnancy) * Subject in a period of exclusion from another study * Subject under administrative or judicial supervision * Subject who cannot be contacted in case of emergency

Primary outcome measure(s)

  • Rate of achievement (success) of all four sections at the extremities — 72 hours +/- 24 hours
    Rate of achievement (success) of all four sections at the extremities for measurements (in mm) of the distances "skin - muscular aponeurosis" and "muscular aponeurosis- periosteum" between 21-24 amenorrhea weeks

Trial sites (2)

FacilityCityRegionStatus
university hospital of Grenoble La Tronche Isère Recruiting
Hopitaux Civils de Lyon - Hôpital Femme Mère Enfant Bron Rhone Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06130592 on ClinicalTrials.gov ↗ ← All trials in France