Autophagy in Paediatric Crohn's Disease

Inclusion Criteria: For Crohn's Disease group : * Age between 6 and 17 inclusive * Patients with a weight \> 25 kg at the time of inclusion * Patients with Crohn's disease requiring ileocolonoscopy (diagnosis or follow-up) * Mild to severe Crohn's disease consistent with PCDAI disease activity score * Patients on nutritional therapy (Modulen/Modulife), corticosteroids, salicylic derivatives, immunosuppressants, biotherapies (anti-TNF, vedolizumab and ustekinumab) or without treatment * Consent form signed by the patient or the holder(s) of parental authority. * Affiliation to a social security scheme or beneficiaries of a similar scheme. For Control group: * Between 6 and 17 years old included * Presenting a weight \> 25 kg at the time of inclusion * Without a diagnosis of Crohn's disease * Requiring evaluation by ileoendoscopy * Consent form signed by the patient or the holder(s) of parental authority. * Affiliation to a social security scheme or beneficiaries of a similar scheme. Exclusion Criteria: * Refusal to participate in the protocol * Intercurrent infection * Ongoing antibiotic treatment * Patient involved in another interventional study protocol including an exclusion period still in progress at pre-inclusion * Pregnant, parturient or breastfeeding women (on questioning) * Persons deprived of their liberty by a judicial or administrative decision * Persons subject to psychiatric care * Persons admitted to a health or social establishment for purposes other than research