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Recruiting Observational

Proteomic Pattern Associated With the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension

NCT05340023 · tracked via the Priya Life Science France tracker
Phase
Observational
Started
2022-11-09
Last updated
2025-11-24

Condition(s) studied

Chronic Thromboembolic Pulmonary Hypertension

Investigational drug(s) / intervention(s)

blood sample →

blood sample: to realize proteomic analysis.

Study summary

Chronic ThromboEmbolic Pulmonary Hypertension (CTEPH) is a rare but severe complication of pulmonary embolism (PE). CTEPH is evoked in patients with persistent dyspnea. According to international guidelines, symptomatic patients with perfusion defects on lung scan and Pulmonary Hypertension (PH)-likely transthoracic echo (TTE) must be evaluated in Pulmonary Hypertension (PH)-centers with right heart catheterism, to confirm or rule out the presence of precapillary Pulmonary Hypertension (PH), and precise the group of Pulmonary Hypertension (PH).

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patient with a suspicion of Chronic thromboembolic pulmonary hypertension (CTEPH) with a combination of a perfusion lung scan and transthoracic perfusion scan and transthoracic echocardiography compatible with the diagnosis (according to French recommendations) * Patients who require a right heart catheterization. * Patient affiliated or entitled to a social security plan * Patient having received informed information about the study informed about the study Exclusion Criteria: * Patient with a normal perfusion lung scan * Person under legal guardianship

Primary outcome measure(s)

  • Proteomic pattern associated with the diagnosis of Chronic thromboembolic pulmonary hypertension (CTEPH) — Day: 0
    Analysis of the final diagnosis retained for the patient : Chronic thromboembolic pulmonary hypertension (CTEPH) (population of interest), pre-capillary Pulmonary Hypertension (PH) other than Chronic thromboembolic pulmonary hypertension (CTEPH), post-capillary Pulmonary Hypertension (PH), no Pulmonary Hypertension (PH).

Trial sites (1)

FacilityCityRegionStatus
CHU de SAINT-ETIENNE Saint-Etienne France Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05340023 on ClinicalTrials.gov ↗ ← All trials in France