Neuroplasticity After Proprioceptive Rehabiliation

Condition(s) studied

Investigational drug(s) / intervention(s)

Vibrations: Sequenced muscle vibrations during 30 min., 3 times a week during 5 weeks

Study summary

Sequences of muscle tendon vibrations allow to reproduce the sensory feedback during movement like locomotion and kinaesthesia. It is known that such a treatment promotes motor recovery after stroke assuming that it enhances neuroplasticity. The aim of the research is to study the activity in cerebrospinal circuitry to evaluate the neuroplastic changes during and after instrumented proprioceptive rehabilitation relying on sequences of muscle vibration in subacute stroke stages.

Eligibility

Primary outcome measure(s)

• Baseline EMG — Evaluation at baseline (4 days before treatment)
  H-reflex and reciprocal inhibition
• Baseline EEG — Evaluation at baseline (4 days before treatment)
  SEP and resting state activity
• EMG change from baseline after 2-week treatment — Evaluation during the 3rd week of treatment
  H-reflex and reciprocal inhibition
• EEG change from baseline after 2-week treatment — Evaluation during the 3rd week of treatment
  SEP and resting state activity
• EMG change after the 5-week treatment — Evaluation 4 days after the end of the 5-week treatment
  H-reflex and reciprocal inhibition
• EEG change after the 5-week treatment — Evaluation 4 days after the end of the 5-week treatment
  SEP and resting state activity

Trial sites (1)

More Institut National de la Santé Et de la Recherche Médicale, France trials in France

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