Training Cognition With Neurofeedback After Stroke

Condition(s) studied

Investigational drug(s) / intervention(s)

Cognitive remediation therapy: Cognitive remediation therapy as treatment as usual

Neuropsychological assessment: Neuropsychological assessment to measure cognitive performances

Real-time functional MRI neurofeedack (rt-fMRI NF): Real-time functional MRI neurofeedack (rt-fMRI NF) is a procedure of brain-machine interface supporting self-regulation of brain activity, with promising results in the treatment of mental disorders. The main objective of the study is to evaluate in a pilot study, the ability of stroke patients to learn to self-regulate their brain activity in a priviledged direction.

fMRI sessions: fMRI sessions but without receiving feedback

Study summary

Post-stroke cognitive impairment (PSCI) is a common source of invisible disability. The actual techniques of cognitive remediation have been reported to have only a small effect, justifying the need to foster research in this field. Real-time functional MRI neurofeedack (rt-fMRI NF) is a procedure of brain-machine interface supporting self-regulation of brain activity, with promising results in the treatment of mental disorders. The main objective of the study is to evaluate in a pilot study, the ability of stroke patients to learn to self-regulate their brain activity in a priviledged direction, using rt-fMRI NF

Eligibility

Primary outcome measure(s)

• Differential CEN-DMN activity and imaging contrast between regulation and rest — Through study training completion, an average of 4 weeks
  Change from baseline to each training session on the CEN-DMN activity during regulation compared with rest, in the experimental and control groups

Trial sites (1)

More University Hospital, Bordeaux trials in France

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