Superb Microvascular Intraocular Tumor Imaging Study (SMITIS)

Condition(s) studied

Investigational drug(s) / intervention(s)

Doppler technology: The study of tumor vascularization can help in the differential diagnosis and follow-up of tumors, and therefore can impact the management of patients with tumors

Study summary

The diagnosis and monitoring of intraocular tumors are based on multimodal imaging in addition to the clinical examination (ultra-widefield retinal imaging, echography, angiography). Nevertheless, it may be difficult in cases of retinal hemorrhage, small tumor size or atypical presentation. The study of microvascular flow (Superb Microvascular Imaging, SMI) of intraocular tumors could improve the confidence of differential diagnosis when evaluating these suspicious lesions, or even determine whether a lesion is benign or malignant by describing the vascularization of the lesion.

The investigators propose to study the microvascular flow patterns of intraocular tumors prior to proton therapy.

Eligibility

Primary outcome measure(s)

• Qualitative description of the intratumoral microvascular flow — Visite 2 - two weeks after Day 0
  Number of visible feeding pedicles
• Qualitative description of the intratumoral microvascular flow — Month 6
  Number of visible feeding pedicles

Trial sites (1)

More Centre Hospitalier Universitaire de Nice trials in France