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Clinical Trials in France / NCT04849754
Recruiting Not applicable

Analysis of the Evolution of SUVmax by Quantitative Analysis Method of Bisphosphonate Scintigraphy

NCT04849754 · tracked via the Priya Life Science France tracker
Sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Phase
Not applicable
Started
2021-02-25
Last updated
2026-08-20

Condition(s) studied

Cardiac Amyloidosis

Investigational drug(s) / intervention(s)

bone scintigraphy

bone scintigraphy: Bone scintigraphy

Study summary

Recently, treatment with tafamidis in patients with cardiac ATTR lead to a significant reduction in mortality. The Perugini score is commonly used on planar bone scans to differentiate cardiac ATTR from other amyloidosis or normal patients but fails to evaluate amyloid burden and patient prognosis. Although semi-quantitative methods have been suggested to evaluate the amyloid burden, there a need for quantitative methods for longitudinal assessment of the disease.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patient, male or female, over 18 years of age * Patient diagnosed with transthyretin cardiac amyloidosis confirmed by scintigraphy * Patient with signed consent Exclusion Criteria: * Patients with systemic AL amyloidosis * Protected patient : major under guardianship, tutorship or other legal protection, deprived of liberty by judicial or administrative decision * Pregnant or breastfeeding woman

Primary outcome measure(s)

  • Measurement of SUVmax by quantitative analysis by bisphosphonate scintigraphy — 6 months

Trial sites (1)

FacilityCityRegionStatus
Hôpital privé Le Bois Lille France Recruiting

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Other trials for the same condition

Description of a Retrospective Cohort of Patients With Transthyretin Cardiac Amyloidosis (ATTR-CA) in Internal Medicine Recruiting
Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure Recruiting
Registre HEAR, Healthcare European Amyloidosis Registry Recruiting
Prevalence of Cardiac Thrombi in Cardiac Amyloidosis Recruiting
Amylo-Shiatsu-Acute-Chronic: Effects of Shiatsu on Symptoms and Quality of Life of Amyloidosis Patients Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04849754 on ClinicalTrials.gov ↗ ← All trials in France