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Clinical Trials in France / NCT04563676
Active, not recruiting Not applicable

Physiopathology and Sequelae of COVID-19 Infection

NCT04563676 · tracked via the Priya Life Science France tracker
Sponsor
Centre Hospitalier Universitaire, Amiens
Phase
Not applicable
Started
2020-09-22
Last updated
2025-05-29

Condition(s) studied

Covid19TSHCortisol

Investigational drug(s) / intervention(s)

blood test →

blood test: covid19 infected patient will have a blood test in order to make an autoimmune assessment (antinuclear antibodies, soluble nuclear anti-antigen, ANCA, antiphospholipid antibodies, FT3, FT4 , TSH, antithyroid antibodies, ACTH cortisol, and creation of a serotheque).

Study summary

The data obtained from Covid-19 infections seem to suggest that the immunogenesis of Covid-19 could in some cases be the result of immune dysregulation. On the other hand, endocrine damage is possible at the tile of Covid-19 infection (mainly thyroid,adrenal, and hypothalamus). These disorders are autoimmune or linked to degeneration.

The main objective is to assess the thyroid function (thyrotropic axis) as well as the corticotropic adrenal function of patients who have had Copvid-19 pneumonia. The secondary objectives is to describe the pathophysiological mechanisms of pulmonary and vasculothrombotic involvement of Covid-19

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * patient having a covid19 infection hospitalized at the Amiens Picardie University Hospital * Patient who is seen in Pneumology consultation for a respiratory assessment at 3 months of his hospitalization (between M2 and M4) to evaluate presence of respiratory sequelae * Patient who agreed to participate in the protocol * Patient affiliated to a Social Security Exclusion Criteria: * patient under guardianship or curators * patient refusing to participate

Primary outcome measure(s)

  • 8-hour cortisol level in patients with Covid19 pneumonia — day 0
    8-hour cortisol level in patients with Covid19 pneumonia will be determined the day of consultation for respiratory sequelae.
  • TSH level in patients with Covid19 pneumonia — day 0
    TSH level in patients with Covid19 pneumonia will be determined the day of consultation for respiratory sequelae.

Trial sites (1)

FacilityCityRegionStatus
CHU Amiens Amiens France

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Other trials for the same condition

COVID-19 Serology and Immunosenescence Active, not recruiting
Covid-19 Effects on Arterial Stiffness and Vascular Aging (CARTESIAN) Recruiting
Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04563676 on ClinicalTrials.gov ↗ ← All trials in France