Acute Heart Failure With Preserved Ejection Fraction - COngestion Discharge Evaluation
Condition(s) studied
Investigational drug(s) / intervention(s)
Clinical examination centered on congestion: Clinical examination centered on congestion (ASCEND, NYHA and Ambrosy Score) will be performed before discharge from hospital
Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography: Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography will be performed before discharge from hospital
Biological: Blood sample retrieved for biological assessment and biobanking: Blood sample collection will be performed before discharge from hospital
Telephone interview: Telephone interview will be performed at 3, 12 months and 24 months after discharge from Hospital
Kansas City Cardiomyopathy Questionnaire (KCCQ): Questionnaire centered on patient's quality of life at discharge and 3, 12 and 24 months after discharge
Study summary
The AHF-CODE preserved study is a prospective, non-randomized, monocenter study performed in patients with heart failure with preserved ejection fraction admitted for worsening heart failure.
The main objective of the AHF-CODE preserved study is to identify congestion markers (clinical, biological and ultrasound) at the end of hospitalization for acute heart failure that are associated with the risk of all cause death or rehospitalization for acute heart failure within 3 months of hospital discharge.
Eligibility
Primary outcome measure(s)
- Rate of all-cause death — 3 months after hospital discharge
composite endpoint : rate of all-cause death or re-hospitalisation for acute heart failure at 3 months after hospital discharge (with outcome 2 and 3) - Rate of re-hospitalisation for acute heart failure — 3 months after hospital discharge
composite endpoint : rate of all-cause death or re-hospitalisation for acute heart failure at 3 months after hospital discharge (with outcome 1 and 3) - Rate of day-hospital or in-home IV diuretics injection for acute HF — 3 months after hospital discharge
composite endpoint : rate of all-cause death or re-hospitalisation for acute heart failure at 3 months after hospital discharge (with outcome 2 and 3)
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| CHRU de Nancy | Vandœuvre-lès-Nancy | France | Recruiting |
More Central Hospital, Nancy, France trials in France
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT04343430 on ClinicalTrials.gov ↗ ← All trials in France