Study to Evaluate the Efficacy of a Polyamine-deficient Diet for Treating Postoperative Pain After Abdominal Surgery
Condition(s) studied
Investigational drug(s) / intervention(s)
Polyamine Deficient Diet: Diet low in polyamines: the estimated calculated dose is 20 times lower that in an usual diet
Study summary
The aim of this study is to evaluate if a polyamine deficient diet started 7 days prior to a major abdominal surgery (eventration cure and digestive continuity) and followed 7 days post-surgery reduces the area under the curve of the numerical pain rating scale in the 72 hours post-surgery.
Eligibility
Primary outcome measure(s)
- To show a 20% decrease of the area under the curve for the numerical pain rating scale in the 72 hours post-operative in the polyamine deficient diet group — 72 hours post-surgery
To show a 20% decrease of the area under the curve for the numerical pain rating scale in the 72 hours post-operative in the polyamine deficient diet group measured every 6 hours in resting position, upon return from the operative room
Trial sites (4)
| Facility | City | Region | Status |
|---|---|---|---|
| CHRU Brest La Cavale Blanche | Brest | France | Recruiting |
| Hôpital Louis Mourier from Ap-HP | Colombes | France | Recruiting |
| CHD Vendée | La Roche-sur-Yon | France | Recruiting |
| CHU Nantes Hôtel Dieu | Nantes | France | Recruiting |
More Nantes University Hospital trials in France
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT04219956 on ClinicalTrials.gov ↗ ← All trials in France