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Clinical Trials in France / NCT04206644
Active, not recruiting Observational

Systemic Sclerosis and Jak Inhibitors : Emphasis on Macrophages

NCT04206644 · tracked via the Priya Life Science France tracker
Sponsor
Rennes University Hospital
Phase
Observational
Started
2021-01-21
Last updated
2023-04-12

Condition(s) studied

Systemic Sclerosis

Investigational drug(s) / intervention(s)

biological analysis

biological analysis: biological analysis of the Concentration of CCL18

Study summary

The Sclero-JAK project aims to assess the impact of a JAK1/2 inhibitor (ruxolitinib) on activation states of monocytes-derived macrophages (MDM) from systemic sclerosis (SSc) patients

Eligibility

Sex
ALL
Min age
18 Years
Max age
18 Years
Healthy volunteers
No
Inclusion Criteria: * patients with systemic sclerosis according to the ACR/EULAR 2013 classification criteria for systemic sclerosis or Patients with systemic lupus according to the ACR2019 classification criteria for systemic lupus * with informed consent for participation to the study Exclusion Criteria: * patients unable to consent * patients with anemia inferior to 7g/dL

Primary outcome measure(s)

  • Concentration of CCL18 in the condition media of MDM from SSc patients — through study completion, an average of 4 year
    at the end of the study

Trial sites (1)

FacilityCityRegionStatus
Rennes University Hospital Rennes France

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Other trials for the same condition

EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases Recruiting
Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) Active, not recruiting
Longitudinal Characterization of Microbial Signature in Systemic Sclerosis Patients Recruiting
Neutrophil Extracellular Traps in Different Forms of Systemic Sclerosis Recruiting
Prospective Cohort of Patients With Systemic Sclerosis at Brest University Hospital With Biobanking Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04206644 on ClinicalTrials.gov ↗ ← All trials in France